General Thoracic and Cardiovascular Surgery

, Volume 65, Issue 4, pp 229–234 | Cite as

Two surgical cases of thymic MALT lymphoma associated with multiple lung cysts: possible association with Sjögren’s syndrome

  • Hiromasa AraiEmail author
  • Michihiko Tajiri
  • Shotaro Kaneko
  • Yoshihiro Kushida
  • Kohei Ando
  • Takayoshi Tachibana
  • Shigeaki Umeda
  • Koji Okudela
  • Shigeru Komatsu
  • Munetaka Masuda
Case Report


Thymic mucosa-associated lymphoid tissue (MALT) lymphoma is rare. Sjögren’s syndrome (SjS) has strong association with thymic MALT lymphoma but the exact etiology is unknown. On the other hand, SjS is characterized by the complication of various lung manifestations, including lung cysts. The mechanism for these lesions is also unknown. But the underlying SjS could result in MALT lymphoma with lung cysts. Herein, we demonstrate two surgical cases of thymic MALT lymphoma associated with multiple lung cysts and the characterization of this rare tumor. During surgery, the tumors were found to be well capsuled and had no adhesion or invasion to the surrounding tissues consistent with its characteristics of low grade malignancy. When thymic MALT lymphoma is suspected clinically, video-assisted thoracoscopic surgery might be the best approach for diagnosis. We propose that radiological findings of a thymic tumor along with lung cysts are an indication of thymic MALT lymphoma.


MALT lymphoma Thymus Sjögren’s syndrome (SjS) Lung cyst Video-assisted thoracoscopic surgery (VATS) 


Compliance with ethical standards

Conflict of interest

The authors declare no conflicts of interest.


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Copyright information

© The Japanese Association for Thoracic Surgery 2016

Authors and Affiliations

  • Hiromasa Arai
    • 1
    Email author
  • Michihiko Tajiri
    • 1
  • Shotaro Kaneko
    • 1
  • Yoshihiro Kushida
    • 1
  • Kohei Ando
    • 1
  • Takayoshi Tachibana
    • 5
  • Shigeaki Umeda
    • 2
  • Koji Okudela
    • 2
  • Shigeru Komatsu
    • 3
  • Munetaka Masuda
    • 4
  1. 1.Department of General Thoracic SurgeryKanagawa Cardiovascular and Respiratory CenterYokohamaJapan
  2. 2.Department of PathologyYokohoma City University Graduate School of MedicineYokohamaJapan
  3. 3.Department of Respiratory MedicineKanagawa Cardiovascular and Respiratory CenterYokohamaJapan
  4. 4.Departoment of SurgeryYokohoma City University Graduate School of MedicineYokohamaJapan
  5. 5.Department of Hematology and Clinical ImmunologyYokohoma City University Graduate School of MedicineYokohamaJapan

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