General Thoracic and Cardiovascular Surgery

, Volume 59, Issue 7, pp 477–482 | Cite as

Management of patients with coronary stents in elective thoracic surgery

  • Makoto Sonobe
  • Toshihiko Sato
  • Fengshi Chen
  • Takuji Fujinaga
  • Tsuyoshi Shoji
  • Hiroaki Sakai
  • Ryo Miyahara
  • Toru Bando
  • Chen-Long Huang
  • Hiroshi Date
Original Article

Abstract

Purpose

Interruption of oral antiplatelet agents for noncardiac surgery places patients who have received coronary stent implantation at high risk of coronary events, including stent thrombosis. We investigated retrospectively perioperative management for patients with coronary stents undergoing thoracic surgery.

Methods

We investigated 38 patients (age, 38–83 years; 33 men and 5 women) who underwent thoracic surgery (35 lung cancer resections and 3 other procedures) after coronary stent implantation at our hospital between January 2006 and August 2010. Data on implanted stents, perioperative medications, and cardiac and hemorrhagic complications were analyzed.

Results

Sirolimus-eluting stents (n = 18) and bare-metal stents (n = 20) were implanted. Regarding oral antiplatelet agents, 21 patients received aspirin, 16 received thienopyridine derivative and aspirin, and 1 received no oral antiplatelet agents. Oral antiplatelet agents were stopped 3–7 days before surgery. Perioperative heparinization was performed in 16 patients. Oral antiplatelet agents were restarted after confirmation of hemostasis and the lack of need for further invasive procedures (median, 4 days after surgery). No major cardiac events including stent thrombosis developed. There were no excessive intraoperative bleeding events related to oral antiplatelet agents or heparin.

Conclusions

In our patients, no coronary events occurred with the short-term stopping of oral antiplatelet agents for thoracic surgery.

Key words

Coronary stent Antiplatelet agent Noncardiac surgery Lung cancer Perioperative management 

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Copyright information

© The Japanese Association for Thoracic Surgery 2011

Authors and Affiliations

  • Makoto Sonobe
    • 1
  • Toshihiko Sato
    • 1
  • Fengshi Chen
    • 1
  • Takuji Fujinaga
    • 1
  • Tsuyoshi Shoji
    • 1
  • Hiroaki Sakai
    • 1
  • Ryo Miyahara
    • 1
  • Toru Bando
    • 1
  • Chen-Long Huang
    • 1
  • Hiroshi Date
    • 1
  1. 1.Department of Thoracic SurgeryKyoto University HospitalKyotoJapan

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