General Thoracic and Cardiovascular Surgery

, Volume 58, Issue 4, pp 205–208 | Cite as

Solitary fibrous tumor of the mediastinum

  • Hiroshi Suehisa
  • Motohiro Yamashita
  • Eisaku Komori
  • Shigeki Sawada
  • Norihiro Teramoto
Case Report

Abstract

An 18-year-old man was referred to our hospital for further evaluation of a right anterior mediastinal tumor that measured 6 cm in diameter. Computed tomography-guided transcutaneous aspiration biopsy was performed, but no definitive diagnosis could be obtained. Because the tumor did not appear to be a high-grade malignant tumor, we undertook resection of the tumor to obtain a definitive diagnosis and provide appropriate treatment. Total thymectomy with tumor resection was performed through a median sternotomy. The tumor was solid, measuring 5.2 × 4.2 × 3.5 cm. The histological diagnosis was solitary fibrous tumor (SFT) arising from the mediastinum. Most extrathoracic SFTs appear to pursue a benign course, although careful long-term follow-up of these patients is necessary because the tumors have been reported to recur or metastasize in some cases.

Key words

Solitary fibrous tumor Extrathoracic Mediastinal tumor 

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References

  1. 1.
    Klemperer P, Rabin CB. Primary neoplasm of the pleura; a report of five cases. Arch Pathol 1931;11:385–412.Google Scholar
  2. 2.
    De Perrot M, Fisher S, Brundler MA, Sekine Y, Keshavjee S. Solitary fibrous tumor of the pleura. Ann Thorac Surg 2002;74:285–293.CrossRefPubMedGoogle Scholar
  3. 3.
    Kouki HS, Koletsis EN, Zolota V, Prokakis C, Apostolakis E, Dougenis D. Solitary fibrous tumor of the lung. Gen Thorac Cardiovasc Surg 2008;56:249–251.CrossRefPubMedGoogle Scholar
  4. 4.
    Baliga M, Flowers R, Heard K, Siddiqi A, Akhtar I. Solitary fibrous tumor of the lung: a case report with a study of the aspiration biopsy, histopathology, immunohistochemistry, and autopsy findings. Diagn Cytopathol 2007;35:239–244.CrossRefPubMedGoogle Scholar
  5. 5.
    De Raet J, Sacre R, Hoorens A, Fletcher C, Lamote J. Malignant giant solitary fibrous tumor of the mediastinum. J Thorac Oncol 2008;3:1068–1070.CrossRefPubMedGoogle Scholar
  6. 6.
    Aoshima H, Oyama K, Ikeda T, Murasugi M, Onuki T, Sawada T. A case of intrapulmonary malignant solitary fibrous tumor with abnormal uptake on FDG-PET. Jpn J Lung Cancer 2008;48:51–55 (in Japanese with English abstract).CrossRefGoogle Scholar
  7. 7.
    Guillou L, Fletcher JA, Fletcher CDM, Mandahl N. Extrapleural solitary fibrous tumor and hemangiopericytoma. In: Fletcher CDM, Unni Krishnan K, Mertens F, editors. WHO classification of tumors; pathology and genetics of tumors of soft tissue and bone. Lyon: IARC Press; 2002. p. 86–90.Google Scholar
  8. 8.
    England DM, Hochholzer L, McCarthy MJ. Localized benign and malignant fibrous tumors of the pleura: a clinicopathologic review of 223 cases. Am J Surg Pathol 1989;13:640–658.PubMedCrossRefGoogle Scholar
  9. 9.
    Hosono Y, Kohno T, Mun M, Makimoto Y, Hamamoto A, Yoshiya T, et al. A 3-ports-VATS resection of a solitary fibrous tumor in the mediastinum: a case report. Jpn J Chest Surg 2007;21:155–159 (in Japanese with English abstract).CrossRefGoogle Scholar
  10. 10.
    Hasegawa T, Matsuno Y, Shimoda T, Hasegawa F, Sano T, Hirohashi S. Extrathoracic solitary fibrous tumors: their histological variability and potentially aggressive behavior. Hum Pathol 1999;30:1464–1473.CrossRefPubMedGoogle Scholar
  11. 11.
    Schirosi L, Lantuejoul S, Cavazza A, Murer B, Yves Brichon P, Migaldi M, et al. Pleuro-pulmonary solitary fibrous tumors: a clinicopathologic, immunohistochemical, and molecular study of 88 cases confirming the prognostic value of de Perrot staging system and p53 expression, and evaluating the role of c-kit, BRAF, PDGFRs (alpha/beta), c-met, and EGFR. Am J Surg Pathol 2008;32:1627–1642.CrossRefPubMedGoogle Scholar

Copyright information

© The Japanese Association for Thoracic Surgery 2010

Authors and Affiliations

  • Hiroshi Suehisa
    • 1
  • Motohiro Yamashita
    • 1
  • Eisaku Komori
    • 1
  • Shigeki Sawada
    • 1
  • Norihiro Teramoto
    • 2
  1. 1.Department of Thoracic SurgeryNational Hospital Organization Shikoku Cancer CenterMatsuyama, EhimeJapan
  2. 2.Department of PathologyNational Hospital Organization Shikoku Cancer CenterMatsuyamaJapan

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