Resected well-differentiated fetal pulmonary adenocarcinoma and summary of 25 cases reported in Japan
- 173 Downloads
We report a case of well-differentiated fetal adenocarcinoma (WDFA), which is a variant of pulmonary blastoma. A 36-year-old man was found to have a tumor shadow in the right middle field of a chest radiograph as part of a mass screening examination, and chest computed tomography (CT) showed a 4.5-cm pulmonary mass in the right lower lobe. A diagnosis of adenocarcinoma of the lung was made based on a CT-guided needle biopsy, and right middle and lower lobectomy and lymph node dissection were performed. The postoperative pathological diagnosis was well-differentiated fetal adenocarcinoma. WDFA has a better prognosis than conventional pulmonary blastoma (biphasic pulmonary blastoma). We summarize the cases of WDFA reported in Japan and review the literature.
Key wordsWell-differentiated fetal adenocarcinoma Pulmonary blastoma Prognosis
Unable to display preview. Download preview PDF.
- 7.Travis, WDColby, TVCorrin, BShimosato, YBrambilla, E eds. 1999Histological typing of lung and pleural tumors. 3rd edition. World Health Organization classification of tumorsIARCLyonGoogle Scholar
- 9.Nakatani, Y, Masudo, K, Miyagi, Y, Inayama, Y, Kawano, N, Tanaka, Y, et al. 2002Aberrant nuclear localization and gene mutation of beta-catenin in low-grade adenocarcinoma of fetal lung type: up-regulation of the Wnt signaling pathway may be a common denominator for the development of tumors that form morulesMod Pathol1561724CrossRefPubMedGoogle Scholar