Journal of the American Oil Chemists' Society

, Volume 93, Issue 10, pp 1399–1406 | Cite as

Synthesis of Fatty Acetoacetates Under Microwave Irradiation Catalysed by Sulfamic Acid in a Solvent-Free System

  • Andressa C. H. Weber
  • Thaís C. Batista
  • Bruno Gonçalves
  • Carolina R. L. Hack
  • Larissa M. Porciuncula
  • Tamara G. M. Treptow
  • Caroline Da R. Montes D’Oca
  • Dennis Russowsky
  • Marcelo G. Montes D’Oca
Original Paper


The 1,3-dicarbonyl compounds are important building blocks to obtain products with various biological activities and technological applications. In this work, we used a simple transesterification method to develop fatty acetoacetates in a solvent-free medium using a green catalyst, sulfamic acid (NH2SO3H), under microwave irradiation. The experimental results demonstrate good yields in a short reaction time (13 min), which makes this method an efficient approach to synthesize fatty acetoacetates from a wide range of saturated, unsaturated, and polyunsaturated long chain fatty alcohols, and ricinoleic derivatives. Experiments of recycling of the catalyst were performed and no decrease in catalytic activity of sulfamic acid was observed.


Castor oil Renewable resources Transesterification reaction 1,3-dicarbonyl compounds Microwave-assisted 



The authors are thankful for financial support from Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), Fundação de Apoio à Pesquisa do Estado do Rio Grande do Sul (FAPERGS/PRONEM), and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq). Fellowships from CAPES (A. C. H. Weber) and CNPq (D. Russowsky and M. G. Montes D’Oca) are also acknowledged.

Compliance with ethical standards

Conflict of interest

The authors declare no conflict of interests.

Supplementary material

11746_2016_2879_MOESM1_ESM.doc (5.5 mb)
Supplementary material 1 (DOC 5581 kb)


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Copyright information

© AOCS 2016

Authors and Affiliations

  • Andressa C. H. Weber
    • 1
  • Thaís C. Batista
    • 1
  • Bruno Gonçalves
    • 1
  • Carolina R. L. Hack
    • 1
  • Larissa M. Porciuncula
    • 1
  • Tamara G. M. Treptow
    • 1
  • Caroline Da R. Montes D’Oca
    • 2
  • Dennis Russowsky
    • 2
  • Marcelo G. Montes D’Oca
    • 1
  1. 1.Laboratório Kolbe de Síntese Orgânica, Escola de Química e AlimentosUniversidade Federal do Rio GrandeRio GrandeBrazil
  2. 2.Laboratório de Sínteses Orgânicas, Instituto de QuímicaUniversidade Federal do Rio Grande do SulPorto AlegreBrazil

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