Management of peripheral arterial disease in the modern era: an internist “Cup of Tea”

  • Marco ProiettiEmail author

Peripheral arterial disease (PAD), intended as the atherosclerotic occlusive disease of the lower extremities, represents a relevant vascular condition which has been estimated to affect more than 200 million people worldwide [1]. Epidemiological data showed how prevalence and incidence sharply increase with age, affecting a substantial proportion of elderly and very elderly subjects (> 20% in subjects > 80 years old), both referring to symptomatic and asymptomatic clinical presentation [1].

In the 2017 European Society of Cardiology (ESC) guidelines on the management of PAD [2] the term ‘peripheral arterial diseases’ has been extended to include a pathological condition of any vascular site. Conversely, to indicate the classical PAD, the term ‘Lower Extremity Arterial Disease’ (LEAD) has been preferred.

To date, the clinical management of patients with symptomatic PAD stands on some pivotal pillars. In the recent issue of the clinical guidelines, the authors established the “best...


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The author declare no conflict of interest related to this paper.

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Copyright information

© Società Italiana di Medicina Interna (SIMI) 2019

Authors and Affiliations

  1. 1.Department of Clinical Sciences and Community HealthUniversity of MilanMilanItaly
  2. 2.Geriatric UnitFondazione IRCCS Ca’ Granda, Ospedale Maggiore PoliclinicoMilanItaly
  3. 3.Liverpool Centre for Cardiovascular ScienceUniversity of Liverpool and Liverpool Heart and Chest HospitalLiverpoolUK

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