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Assessment of deep venous thrombosis in the lower extremity in Behçet’s syndrome: MR venography versus Doppler ultrasonography

  • Burcin Tutar
  • Fatih Kantarci
  • Osman Serdal Cakmak
  • Hasan Yazici
  • Emire SeyahiEmail author
IM - ORIGINAL
  • 19 Downloads
Part of the following topical collections:
  1. Behcet disease
  2. Behcet disease
  3. Behcet disease

Abstract

Lower extremity venous thrombosis (DVT) is the most common vascular manifestation of Behçet’s syndrome (BS). Currently, Doppler ultrasonography (USG) is the most commonly preferred imaging modality in the diagnosis and follow-up of patients with acute and chronic DVT. Magnetic resonance (MR) venography, a quick and a non-invasive imaging modality, is successfully used to detect DVT in various settings. We had been unaware of studies with MR venography in BS. The aim of this study is to compare the diagnostic value of true fast imaging with steady-state precession magnetic resonance (True-FISP MR) venography and Doppler USG in the assessment of chronic DVT among patients with BS. 28 BS patients with chronic lower extremity DVT were studied. Common femoral (CFV) and femoral vein (FV) on both right and left sides were examined for the presence of thrombosis, recanalisation, collaterals and reflux. There are findings of chronic DVT in all Doppler USG images of 28 patients (45 of 56 FV and 35 of 56 CFV), while MR venography detects chronic thrombotic changes in 26/28 (93%) patients (43 of 52 FV and 28 of 52 CFV). Collateral veins are detected in 19 patients (19/28) with MR venography, whereas they are present in only 7 (7/28) with USG (P = 0.003). Furthermore, patients with severe post-thrombotic syndrome are more likely to have collateral formation on the MR compared to those without (12/14 vs 7/14; P = 0.043). Among patients with BS, MR venography might be an alternative or additional method to detect chronic thrombosis in the lower extremities.

Keywords

Behçet’s syndrome Lower extremity venous thrombosis MR venography Color Doppler USG 

Abbreviations

CFV

Common femoral vein

FV

Femoral vein

DVT

Deep-vein thrombosis

USG

Ultrasonography

MR

Magnetic resonance

BS

Behçet’s syndrome

CV

Contrast venography

CDUS

Compression Doppler ultrasonography

USG

Ultrasonography

SFA

Superficial femoral artery

True-FISP MR

True fast imaging with steady-state precession (FISP) MR venography

VCSS

Venous clinical severity scoring

CEAP

Clinical, etiologic, anatomical, and by patho-physiological classification

PTS

Post-thrombotic syndrome

Notes

Author contributions

All the authors had access to the data and participated in writing of the manuscript.

Funding

None.

Compliance with ethical standards

Conflict of interest

Authors declare that they have no conflict of interest.

Statements on human and animal rights

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Oral informed consent was obtained from all the patients.

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Copyright information

© Società Italiana di Medicina Interna (SIMI) 2019

Authors and Affiliations

  • Burcin Tutar
    • 1
  • Fatih Kantarci
    • 1
  • Osman Serdal Cakmak
    • 2
  • Hasan Yazici
    • 3
  • Emire Seyahi
    • 3
    Email author
  1. 1.Department of Radiology, Cerrahpaşa Medical FacultyUniversity of IstanbulIstanbulTurkey
  2. 2.Department of Medicine, Cerrahpaşa Medical FacultyUniversity of IstanbulIstanbulTurkey
  3. 3.Division of Rheumatology, Department of Internal Medicine, Cerrahpaşa Medical FacultyUniversity of IstanbulIstanbulTurkey

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