Fluid intake and chronic kidney disease: effect of coaching an increase in fluid intake on kidney function decline
- 72 Downloads
Despite the commonly held view that drinking more water is beneficial to kidney function, little scientific data exist that support this belief. In observational studies, increased water intake is associated with a mortality reduction or with a reduced risk of developing chronic kidney disease (CKD) in the general population [1, 2, 3]. In animal models of CKD who underwent nearly complete bilateral nephrectomy, it is observed that an increased water consumption suppresses plasmatic antidiuretic hormone (ADH) concentration, reduces levels of copeptin  and improves kidney function . However, the effects of hyperhydration on kidney function of human patients with CKD have not yet been elucidated.
Clark et al. conducted a randomized clinical trial evaluating the effect of coaching to increase water intake on kidney function in adults with CKD. Inclusion criteria were age between 18 years and 80 years, ability to provide informed consent and the will to complete...
Compliance with ethical standards
Conflict of interest
The authors declare that they have no conflict of interest.
Statement of human and animal rights
This article does not contain any studies with human and animals performed by any of the authors.
For this type of study, formal consent is not required.