Internal and Emergency Medicine

, Volume 7, Supplement 1, pp 15–16 | Cite as

Mollaret’s meningitis: 65 years of history

  • Francois Abi-Fadel
  • Katarzyna Harasiuk
  • Michael Ng

Benign recurrent meningitis was first described by Pierre Mollaret in 1944 [1]. It is characterized by greater than three episodes of fever, headache and meningismus lasting 2–5 days [2, 5]. We describe a case of a patient presenting with recurrent aseptic meningitis. The diagnosis was only ascertained after the 4th admission.

A 57-year-old woman presented to the emergency department (ED) for headache and nausea lasting 2 weeks. She had near-syncope, vomiting, chills, neck stiffness and dizziness, but denied any fever. The headache was progressive and bi-frontal. Her past medical history was significant for depression on sertraline, back pain, and previous episodes of meningitis found to be aseptic in nature. Also noted was a history of lupus erythematosus controlled with no ongoing therapy. The social history was negative for smoking, alcohol or drugs.

On admission, the vital signs were stable, there was no fever, and a complete physical examination was normal except for the...


Meningitis Cerebral Spinal Fluid Aseptic Meningitis Lymphocytic Pleocytosis Recurrent Meningitis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Conflict of interest



  1. 1.
    Mollaret P (1944) La meningiteendothelio-leukocytaire multi-recurrente. Rev Neurol Paris 76:57–67Google Scholar
  2. 2.
    Pearce JM (2008) Mollaret’s meningitis. Eur Neurol 60(6):316–317PubMedCrossRefGoogle Scholar
  3. 3.
    Picard FJ, Dekaban GA, Silva J, Rice GP (1993) Mollaret’s meningitis associated with herpes simplex type 2 infection. Neurology 43(9):1722–1727PubMedGoogle Scholar
  4. 4.
    Stoppe G, Stark E, Patzold U (1987) Mollaret’s meningitis: CSF-immunocytological examinations. J Neurol 234(2):103–106PubMedCrossRefGoogle Scholar
  5. 5.
    Prandota J (2009) Mollaret meningitis may be caused by reactivation of latent cerebral toxoplasmosis. Int J Neurosci 119(10):1655–1692PubMedCrossRefGoogle Scholar

Copyright information

© SIMI 2011

Authors and Affiliations

  • Francois Abi-Fadel
    • 1
    • 4
  • Katarzyna Harasiuk
    • 2
  • Michael Ng
    • 3
  1. 1.Department of Medicine, Division of Pulmonary and Critical Care Medicine, Downstate Medical CenterState University of New YorkBrooklynUSA
  2. 2.Department of Medicine, Hospitalist DivisionStaten Island University HospitalStaten IslandUSA
  3. 3.Division of NeurologyStaten Island University HospitalStaten IslandUSA
  4. 4.Staten IslandUSA

Personalised recommendations