Internal and Emergency Medicine

, Volume 6, Issue 3, pp 221–226 | Cite as

Tako-tsubo cardiomyopathy: is there a preferred time of onset?

  • Eduardo Bossone
  • Rodolfo Citro
  • Kim A. Eagle
  • Roberto Manfredini
IM - Original

Abstract

The occurrence of major cardiovascular events is not randomly distributed over time, but exhibits chronobiological patterns, i.e., circadian, weekly, or seasonal. No systematic studies on the temporal preference of onset of Tako-tsubo cardiomyopathy (TTC) are known. We performed a computer-assisted search of the literature (from 2000 to January 2010), with the following search terms: transient left ventricular apical ballooning syndrome, takotsubo-like left ventricular dysfunction, ampulla cardiomyopathy, tako-tsubo or takotsubo cardiomyopathy, tako-tsubo, apical ballooning. Criteria for publication inclusion were (a) reporting of original data, (b) inclusion of at least 30 or more cases, (c) adherence to the requested diagnostic criteria for TTC. We focused on studies including in their purposes the “time of onset” of events. Out of the 19 studies found, 7 (4 from Europe, 1 each from Asia, Australia and USA) specifically addressed this aspect. A circadian (morning) and a seasonal (summer) higher frequency of events was found. TTC seems to exhibit a temporal variation of onset, with preferred peaks during morning and summer. Stress and catecholamines, also according to their temporal organization, might play a pivotal role. The demonstration of time frames characterized by highest frequency of occurrence might help to try to ensure maximal protection during particularly vulnerable periods.

Keywords

Circadian rhythm Seasons Tako-tsubo cardiomyopathy 

References

  1. 1.
    Prasad A, Lerman A, Rihal CS (2008) Apical ballooning syndrome (Tako-tsubo or stress cardiomyopathy): a mimic of acute myocardial infarction. Am Heart J 155:408–417PubMedCrossRefGoogle Scholar
  2. 2.
    Nef HM, Mollmann H, Akashi YI, Hamm CW (2010) Mechanisms of stress (Takotsubo) cardiomyopathy. Nat Rev Cardiol 7:187–193PubMedCrossRefGoogle Scholar
  3. 3.
    Muller JE, Stone PH, Turi ZG et al (1985) Circadian variation in the frequency of onset of acute myocardial infarction. N Engl J Med 313:1315–1322PubMedCrossRefGoogle Scholar
  4. 4.
    Manfredini R, Boari B, Smolensky MH et al (2005) Seasonal variation in onset of myocardial infarction: a 7-year single-center study in Italy. Chronobiol Int 22:1097–1111Google Scholar
  5. 5.
    Willich SN, Lowel H, Lewis M et al (1994) Weekly variation of acute myocardial infarction: increased Monday risk in the working population. Circulation 90:87–93PubMedGoogle Scholar
  6. 6.
    Casetta I, Granieri E, Fallica E et al (2002) Patient demographic and clinical features and circadian variation in onset of ischemic stroke. Arch Neurol 59:48–53PubMedCrossRefGoogle Scholar
  7. 7.
    Manfredini R, Casetta I, Paolino E et al (2001) Monday preference in onset of ischemic stroke. Am J Med 111:401–403PubMedCrossRefGoogle Scholar
  8. 8.
    Mehta RH, Manfredini R, Hassan F et al (2002) Chronobiological patterns of acute aortic dissection. Circulation 106:1110–1115PubMedCrossRefGoogle Scholar
  9. 9.
    Gianni M, Dentali F, Grandi AM et al (2006) Apical ballooning syndrome or takotsubo cardiomyopathy: a systematic review. Eur Heart J 27:1523–1529PubMedCrossRefGoogle Scholar
  10. 10.
    Mansecal N, El Mahmoud R, Dubourg O (2010) Occurrence of Tako-tsubo cardiomyopathy and chronobiological variation. J Am Coll Cardiol 55:500–501CrossRefGoogle Scholar
  11. 11.
    Regnante R, Zuzek RW, Weinsier SB et al (2009) Clinical characteristics and four-year outcomes of patients in the Rhode Island takotsubo cardiomyopathy registry. Am J Cardiol 103:1015–1019PubMedCrossRefGoogle Scholar
  12. 12.
    Vidi V, Rajesh V, Singh PP et al (2009) Clinical characteristics of tako-tsubo cardiomyopathy. Am J Cardiol 104:578–582PubMedCrossRefGoogle Scholar
  13. 13.
    Manfredini R, Citro R, Previtali M et al (2009) Summer preference in the occurrence of takotsubo cardiomyopathy is independent of age. J Am Geriatr Soc 57:1509–1511PubMedCrossRefGoogle Scholar
  14. 14.
    Citro R, Previtali M, Bovelli D et al (2009) Chronobiological patterns of onset of tako-tsubo cardiomyopathy. J Am Coll Cardiol 54:180–181PubMedCrossRefGoogle Scholar
  15. 15.
    Eshtehardi P, Koestner SC, Adorjan P et al (2009) Transient apical ballooning syndrome—clinical characteristics, ballooning pattern, and long-term follow-up in a Swiss population. Int J Cardiol 135:370–375PubMedCrossRefGoogle Scholar
  16. 16.
    Jabara R, Gadesam R, Pendyala L et al (2009) Comparison of the clinical characteristics of apical and non-apical variants of “broken heart” (takotsubo) syndrome in the United States. J Invasive Cardiol 21:216–222PubMedGoogle Scholar
  17. 17.
    Dib C, Asirvatham S, Elesber A et al (2009) Clinical correlates and prognostic significance of electrocardiographic abnormalities in apical ballooning syndrome (Takotsubo/stress-induced cardiomyopathy). Am Heart J 157:933–938PubMedCrossRefGoogle Scholar
  18. 18.
    Ortak J, Khattab K, Barante M et al (2009) Evolution of cardiac autonomic nervous activity indices in patients presenting with transient left ventricular apical ballooning. Pacing ClinElectrophysiol 32(Suppl 1):S21–S25CrossRefGoogle Scholar
  19. 19.
    Kurisu S, Inoue I, Kawagoe T et al (2009) Prevalence of incidental coronary artery disease in tako-tsubo cardiomyopathy. Coron Artery Dis 20:214–218PubMedCrossRefGoogle Scholar
  20. 20.
    Nunez-Gil IJ, Fernandez-Ortiz A, Perez-Isla L et al (2008) Clinical and prognostic comparison between left ventricular transient dyskinesia and a first non-ST-segment elevation acute coronary syndrome. Coron Artery Dis 19:449–453PubMedCrossRefGoogle Scholar
  21. 21.
    El Mahmoud R, Mansencal N, Pilliere R et al (2008) Prevalence and characteristics of left ventricular outflow tract obstruction in tako-tsubo syndrome. Am Heart J 156:543–548PubMedCrossRefGoogle Scholar
  22. 22.
    Elesber A, Prasad A, Lennon R et al (2007) Four-year recurrence rate and prognosis of the apical ballooning syndrome. J Am Coll Cardiol 50:448–452PubMedCrossRefGoogle Scholar
  23. 23.
    Kurowski V, Kaiser A, von Hof K et al (2007) Apical and midventricular transient left ventricular dysfunction syndrome (tako-tsubo cardiomyopathy): frequency, mechanisms, and prognosis. Chest 132:809–816PubMedCrossRefGoogle Scholar
  24. 24.
    Kurisu S, Inoue I, Kawagoe T et al (2007) Circadian variation in the occurrence of tako-tsubo cardiomyopathy: comparison with acute myocardial infarction. Int J Cardiol 115:270–271PubMedCrossRefGoogle Scholar
  25. 25.
    Abdulla I, Kay S, Mussap C et al (2007) Apical sparing in tako-tsubo cardiomyopathy. Intern Med J 36:414–418CrossRefGoogle Scholar
  26. 26.
    Hertting K, Krause K, Harle T et al (2006) Transient left ventricular apical ballooning in a community hospital in Germany. Int J Cardiol 112:282–288PubMedCrossRefGoogle Scholar
  27. 27.
    Kurisu S, Sato H, Kawagoe T et al (2002) Tako-tsubo-like left ventricular dysfunction with ST-segment elevation: a novel cardiac syndrome mimicking acute myocardial infarction. Am Heart J 143:448–455PubMedCrossRefGoogle Scholar
  28. 28.
    Tsuchihashi K, Ueshima K, Uchida T et al (2001) Transient left ventricular apical ballooning without coronary artery stenosis: a novel heart syndrome mimicking acute myocardial infarction. Angina Pectoris-Myocardial Infarction Investigations in Japan. J Am Coll Cardiol 38:11–18PubMedCrossRefGoogle Scholar
  29. 29.
    Manfredini R, Citro R, Previtali M et al (2010) Monday preference in onset of takotsubo cardiomyopathy. Am J Emerg Med 28:715–719PubMedCrossRefGoogle Scholar
  30. 30.
    Lyon AR, Rees PSC, Prasad S et al (2008) Stress (Takotsubo) cardiomyopathy–a novel pathophysiological hypothesis to explain catecholamine-induced acute myocardial stunning. Nat Clin Pract Cardiovasc Med 5:22–29PubMedCrossRefGoogle Scholar
  31. 31.
    Wittstein IS, Thiemann DR, Lima JAC et al (2005) Neurohumoral features of myocardial stunning due to sudden emotional stress. N Engl J Med 352:539–548PubMedCrossRefGoogle Scholar
  32. 32.
    Descovich GC, Montalbetti N, Kiahl JF et al (1974) Age and catecholamine rhythms. Chronobiologia 1:163–171PubMedGoogle Scholar
  33. 33.
    Hansen AM, Garde AH, Skovgaard LT et al (2001) Seasonal and biological variation of urinary epinephrine, norepinephrine, and cortisol in healthy women. Clin Chim Acta 309:25–35PubMedCrossRefGoogle Scholar
  34. 34.
    Van Cauter E, Leproult R, Kupfer DJ (1996) Effects of gender and age on the levels and circadian rhythmicity of plasma cortisol. J Clin Endocrinol Metab 81:2468–2473PubMedCrossRefGoogle Scholar
  35. 35.
    Rosengren A, Hawken S, Ounpuu S et al (2004) Association of psychosocial risk factors with risk of acute myocardial infarction in 11, 119 cases and 13, 646 controls from 52 countries (the INTERHEART study): case-control study. Lancet 364:953–962PubMedCrossRefGoogle Scholar
  36. 36.
    Roohafza H, Talaei M, Sadeghi M et al (2010) Association between acute and chronic life events on acute coronary syndrome: a case-control study. J Cardiovasc Nurs 25:E1–E7PubMedGoogle Scholar
  37. 37.
    Goddard AW, Ball SG, Martinez J et al (2010) Current perspectives of the roles of the central norepinephrine system in anxiety and depression. Depress Anxiety 27:339–350PubMedCrossRefGoogle Scholar
  38. 38.
    Matthews K, Schwartz J, Cohen S, Seeman T (2006) Diurnal cortisol decline is related to coronary calcification: CARDIA study. Psychosom Med 68:657–661PubMedCrossRefGoogle Scholar
  39. 39.
    Young ME (2003) Circadian rhythms in cardiac gene expressions. Curr Hypertens Rep 5:445–453PubMedCrossRefGoogle Scholar
  40. 40.
    Nonaka H, Emoto N, Ikeda K et al (2001) Angiotensin II induces circadian genes expression of clock genes in cultured vascular smooth muscle cells. Circulation 104:1746–1748PubMedCrossRefGoogle Scholar
  41. 41.
    Durgan JD, Hotze MA, Tomlin TM et al (2005) The intrinsic circadian clock within the cardiomyocyte. Am J Physiol Heart Circ Physiol 289:H1530–H1541PubMedCrossRefGoogle Scholar
  42. 42.
    Curtis AM, Cheng Y, Kapoor S et al (2007) Circadian variation of blood pressure and the vascular response to asynchronous stress. Proc Natl Acad Sci USA 104:3450–3455PubMedCrossRefGoogle Scholar
  43. 43.
    Manfredini R, Boari B, Salmi R et al (2007) Circadian rhythm effects on cardiovascular and other stress-related events. In: Fink G, ed. Encyclopedia of Stress, 2nd ed. Oxford Academic Press; vol 1, pp 500–505Google Scholar
  44. 44.
    Ueyama T, Senba E, Kasamatsu K et al (2003) Molecular mechanism of emotional stress-induced and catecholamine-induced heart attack. J Cardiovasc Pharmacol 41(suppl. 1):S115–S118PubMedGoogle Scholar
  45. 45.
    Trio O, de Gregorio C, Andò G (2010) Myocardial dysfunction after subarachnoid haemorrhage and tako-tsubo cardiomyopathy: a differential diagnosis? Ther Adv Cardiovasc Dis 4:105–107PubMedCrossRefGoogle Scholar
  46. 46.
    Berman M, Ali A, Ashley E et al (2010) Is stress cardiomyopathy the underlying cause of ventricular dysfunction associated with brain death? J Heart Lung Transplant (Epub ahead of print)Google Scholar
  47. 47.
    Gallerani M, Portaluppi F, Maida G et al (1996) Circadian and circannual rhythmicity in the occurrence of subarachnoid hemorrhage. Stroke 27:1793–1797PubMedGoogle Scholar
  48. 48.
    Casetta I, Granieri E, Portaluppi F, Manfredini R (2002) Circadian variability in hemorrhagic stroke. JAMA 287:1266–1267PubMedCrossRefGoogle Scholar
  49. 49.
    Mehta RH, Manfredini R, Bossone E et al (2005) The winter peak in occurrence of acute aortic dissection is independent of the climate. Chronobiol Int 22:72–729Google Scholar
  50. 50.
    Zanobetti M, Vicidomini S, Conti A et al (2010) An atypical case of inverted Tako-tsubo syndrome: case report and review of the literature. Intern Emerg Med 5:215–219PubMedCrossRefGoogle Scholar

Copyright information

© SIMI 2010

Authors and Affiliations

  • Eduardo Bossone
    • 1
  • Rodolfo Citro
    • 2
  • Kim A. Eagle
    • 3
  • Roberto Manfredini
    • 4
  1. 1.Department of Cardiac SurgeryI.R.C.C.S. Policlinico San Donato, San Donato MilaneseMilanItaly
  2. 2.Cardiology DepartmentUniversity Hospital “San Giovanni di Dio e Ruggi d’Aragona”SalernoItaly
  3. 3.University of Michigan Cardiovascular CenterAnn ArborUSA
  4. 4.Department of Clinical and Experimental Medicine, Clinica Medica and Vascular Diseases CenterUniversity of FerraraFerraraItaly

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