Journal of Acupuncture and Tuina Science

, Volume 14, Issue 6, pp 420–425 | Cite as

Umbilicus application with Chinese medicine for chronic diarrhea due to food intolerance in kids: a multicenter randomized trial

  • Jian Shen (沈健)
  • Jian-jie Chen (陈建杰)
  • Li Chen (陈黎)
  • Bi-meng Zhang (张必萌)
  • Jun Zhao (赵鋆)
  • Qing-yan Ye (叶青艳)
  • Ling-wan Kong (孔令万)
Clinical Study
  • 21 Downloads

Abstract

Objective

To observe the clinical efficacy of umbilicus application with Chinese medicine in treating children’s chronic diarrhea due to food intolerance and the value of healthy diet education.

Methods

Eighty kids with chronic diarrhea due to food intolerance were recruited from multiple centers and divided by using the random number table into a treatment group of 40 cases and a control group of 40 cases. For both groups, based on the level of serum food-specific immunoglobulin G (Ig-G), the patients were given unified diet following the healthy diet guidance: safe, alternate, and forbidden, while the treatment group was additionally given umbilicus application with Chinese medicine. The therapeutic efficacy and symptom score of traditional Chinese medicine (TCM) were observed and compared respectively after 1-week, 2-week, 4-week, and 12-week treatment.

Results

The diarrhea symptoms and coupled symptoms scores dropped significantly in the two groups after treatment (all P<0.05), and the inter-group comparisons also showed statistical significances (P<0.05). The total effective rate was 97.5% in the treatment group versus 77.5% in the control group, and the inter-group difference was statistically significant (P<0.05).

Conclusion

The healthy diet guidance based on the food intolerance test is effective in helping treat diarrhea, while umbilicus application with Chinese medicine works better in treating diarrhea for kids with chronic diarrhea due to food intolerance and can significantly enhance the therapeutic efficacy.

Keywords

Acupoint Therapy Point Shenque (CV 8) Drugs Chinese Herbal Application Therapy Administration on Umbilicus Diarrhea Children Preschool 

中药敷脐治疗食物不耐受型儿童慢性腹泻多中心随机观察

摘要

目的

观察中药脐部贴敷对食物不耐受型儿童慢性腹泻患者的临床疗效及饮食健康教育的价值。

方法

将来自多中心的80 例食物不耐受型儿童慢性腹泻患者根据随机数字表分为治疗组40 例和对照组40 例。两组均 根据患儿血清中食物特异性IgG 抗体浓度, 分别采取统一的“安全进食”、“轮替”、“忌食”的健康饮食指导, 治 疗组患儿给予中药脐部贴敷治疗。治疗1 星期、2 星期、4 星期及12 星期后观察并比较两组疗效及中医症状评 分变化。

结果

治疗后两组患者的症状评分均明显下降, 与本组治疗前有统计学差异(均P<0.05), 组间差异亦具 有统计学意义(P<0.05)。对照组总有效率为77.5%, 治疗组总有效率为97.5%, 两组总有效率差异有统计学意义 (P<0.05)。

结论

根据食物不耐受检测结果对患儿进行健康饮食指导止泻有效, 中药脐部贴敷对食物不耐受型儿 童慢性腹泻具有更好的止泻作用, 可显著提高疗效。

关键词

穴位疗法 穴 神阙 中草药 敷贴疗法 敷脐 腹泻 儿童 学龄前 

中图分类号

R245.8 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Notes

Acknowledgements

This work was supported by the Key Special Program of Science and Technology During the National Twelfth Five-year Plan (国家“十二五”科技重大专项项目, No. 2012ZX10005004-003); National Natural Science Foundation of China (国家自然科学基金项目, No. 81302924); Program of Shanghai Science and Technology Committee (上海市科委项目, No. 15401971100); Special Plan of Shanghai Chinese Medicine Experts [上海市中医 药(中医专科)专门人才计划, No. ZY3-RCPY-3-1027].

References

  1. [1]
    Han Y, Kim J, Ahn K. Food allergy. Korean J Pediatr, 2012, 55(5): 153–158.CrossRefPubMedPubMedCentralGoogle Scholar
  2. [2]
    Patel NJ, Jenzarli A. Does food intolerance play a role in recurrent respiratory papillomatosis? Int Rorum Allergy Rhinol, 2012, 2(1): 85–88.CrossRefGoogle Scholar
  3. [3]
    Gibson PR. Food intolerance in functional bowel disorders. J Gastroenterol Hepatol, 2011, 26(Suppl 3): 128–131.CrossRefPubMedGoogle Scholar
  4. [4]
    Zugasti Murillo A. Food intolerance. Endocrinol Nutr, 2009, 56(5): 241–250.CrossRefPubMedGoogle Scholar
  5. [5]
    Guo H, Jiang T, Wang JL, Chang YC, Guo H, Zhang WH. The value of eliminating foods according to food-specific immunoglobulin G antibodies in irritable bowel syndrome with diarrhoea. J Int Med Res, 2012, 40(1): 204–210.CrossRefPubMedGoogle Scholar
  6. [6]
    Eswaran S, Tack J, Chey WD. Food: the forgotten factor in the irritable bowel syndrome. Gastroenterol Clin North Am, 2011, 40(1): 141–162.CrossRefPubMedGoogle Scholar
  7. [7]
    Abraham S, Kellow J. Exploring eating disorder quality of life and functional gastrointestinal disorders among eating disorder patients. J Psychosom Res, 2011, 70(4): 372–377.CrossRefPubMedGoogle Scholar
  8. [8]
    Nery J, Goudez R, Biourge V, Tournier C, Leray V, Martin L, Thorin C, Nguyen P, Dumon H. Influence of dietary protein content and source on colonic fermentative activity in dogs differing in body size and digestive tolerance. J Anim Sci, 2012, 90(8): 2570–2580.CrossRefPubMedGoogle Scholar
  9. [9]
    Hang I, Rinttila T, Zentek J, Kettunen A, Alaja S, Apajalahti J, Harmoinen J, Vos WM, Spillmann T. Effect of high contents of dietary animal-derived protein or carbohydrates on canine faecal microbiota. BMC Vet Res, 2012, 8: 90.CrossRefPubMedPubMedCentralGoogle Scholar
  10. [10]
    Uauy R, Stringel G, Thomas R, Quan R. Effect of dietary nucleosides on growth and maturation of the developing gut in the rat. J Pediatr Gastroenterol Nutr, 1990, 10(4): 497–503.CrossRefPubMedGoogle Scholar
  11. [11]
    Rouf K, White L, Evans K. A qualitative investigation into the maternal experience of having a young child with severe food allergy. Clin Child Psychol Psychiatry, 2012, 17(1): 49–64.CrossRefPubMedGoogle Scholar
  12. [12]
    Hu YM, Jiang ZF. Practical Pediatrics of Zhu Fu-tang. 7th Edition. Beijing: People’s Medical Publishing House, 2002: 1286–1299.Google Scholar
  13. [13]
    State Administration of Traditional Chinese Medicine. Criteria of Diagnosis and Therapeutic Effects of Diseases and Syndromes in Traditional Chinese Medicine. Nanjing: Nanjing University Press, 1994: 79.Google Scholar
  14. [14]
    Fang SH. China diagnostic and treatment protocol for diarrhea. Zhongguo Shiyong Erke Zazhi, 1998, 13(6): 381.Google Scholar
  15. [15]
    Ministry of Health of the People’s Republic of China. Guiding Principles for Clinical Study of New Chinese Medicines. Beijing: China Medical Science Press, 2002: 139–142.Google Scholar
  16. [16]
    Wu QB, Ye JX, Ding YF, Zhang F. Clinical significance of food allergen-specific IgG antibody detection in chronic gastrointestinal disease. J Clin Pediatr, 2006, 24(10): 800–802.Google Scholar
  17. [17]
    Whorwell P, Lea R. Dietary treatment of the irritable bowel syndrome. Curr Treat Options Gastroenterol, 2004, 7(4): 307–316.CrossRefPubMedGoogle Scholar
  18. [18]
    Kong CZ. The umbilicus treatment of pediatric clinical research of children’s rotavirus enteritis (cold wetness type) with Wen Chang Zhi Xie Powder. Jinan: Master Thesis of Shandong University of Traditional Chinese Medicine, 2012.Google Scholar

Copyright information

© Shanghai Research Institute of Acupuncture and Meridian and Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  • Jian Shen (沈健)
    • 1
  • Jian-jie Chen (陈建杰)
    • 1
  • Li Chen (陈黎)
    • 2
  • Bi-meng Zhang (张必萌)
    • 3
  • Jun Zhao (赵鋆)
    • 1
  • Qing-yan Ye (叶青艳)
    • 1
  • Ling-wan Kong (孔令万)
    • 2
  1. 1.Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghaiChina
  2. 2.Shanghai Baoshan District Hospital of Integrated Chinese and Western MedicineShanghaiChina
  3. 3.Shanghai First People’s HospitalShanghai Jiaotong University School of MedicineShanghaiChina

Personalised recommendations