Côlon & Rectum

, Volume 6, Issue 1, pp 1–2

Impact de la réponse immune dans le cancer du côlon: des perspectives encourageantes

Éditorial / Editorial

Références

  1. 1.
    Pages F, Berger A, Camus M, et al (2005) Effector memory T cells, early metastasis, and survival in colorectal cancer. N Engl J Med 353:2654–2666PubMedCrossRefGoogle Scholar
  2. 2.
    Galon J, Costes A, Sanchez-Cabo F, et al (2006) Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 313:1960–1964PubMedCrossRefGoogle Scholar
  3. 3.
    Pages F, Kirilovsky A, Mlecnik B, et al (2011) In situ cytotoxic and memory T cells predict outcome in patients with early-stage colorectal Cancer. Cancer Res 4:1263–1271Google Scholar
  4. 4.
    Mlecnik B, Tosolini M, Kirilovsky A, et al (2011) Histopathologic-based prognostic factors of colorectal cancers are associated with the state of the local immune reaction. J Clin Oncol 29:610–618PubMedCrossRefGoogle Scholar
  5. 5.
    Sargent DJ, Marsoni S, Monges G, et al (2010) Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer. J Clin Oncol 28:3219–3226PubMedCrossRefGoogle Scholar
  6. 6.
    Broussard E, Disis M (2011) TNM staging in colorectal cancer: T is for T cell and M is for memory. J Clin Oncol 29: 601–609PubMedCrossRefGoogle Scholar
  7. 7.
    Halama N, Michel S, Kloor M, et al (2011) Localization and density of immune cells in the invasive margin of human metastatic colorectal cancer are prognostic for response to chemotherapy. Cancer Res 71:5670–5677PubMedCrossRefGoogle Scholar
  8. 8.
    Fridman WH, Galon J, Pagès F, et al (2011) Prognostic and predictive impact of intra- and peritumoral immune infiltrates. Cancer Res 71:5601–5605PubMedCrossRefGoogle Scholar
  9. 9.
    Ogino S, Galon J, Fuchs CS, et al (2011) Cancer immunologyanalysis of host and tumor factors for personalized medicine. Nat Rev Clin Oncol 8:711–719PubMedCrossRefGoogle Scholar

Copyright information

© Springer Verlag France 2012

Authors and Affiliations

  1. 1.Service de pathologieCRLC Val d’AurelleMontpellier cedex 5France

Personalised recommendations