Frontiers of Materials Science in China

, Volume 4, Issue 2, pp 132–138 | Cite as

The influence of HF treatment on corrosion resistance and in vitro biocompatibility of Mg-Zn-Zr alloy

  • Xin-Yu Ye
  • Min-Fang ChenEmail author
  • Chen You
  • De-Bao Liu
Research Article


The samples made of a Mg-2.5wt.%Zn-0.5wt.%Zr alloy were immersed in the 20% hydrofluoric acid (HF) solution at room temperature for different time, with the aim of improving the properties of magnesium (Mg) alloy in applications as biomaterials. The corrosion resistance and in vitro biocompatibility of untreated and fluoride-coated samples were investigated. The results show that the optimum process is to immerse Mg alloys in the 20% HF solution for 6 h. After the immersion, a dense magnesium fluoride (MgF2) coating of 0.5 μm was synthesized on the surface of Mg-Zn-Zr alloy. Polarization tests recorded a reduction in the corrosion current density from 2.10 to 0.05 μA/cm2 due to the MgF2 protective coating. Immersion tests in the simulated body fluid (SBF) also reveal a much milder corrosion on the fluoride-coated samples, and its corrosion rate was calculated to be 0.05 mm/yr. Hemolysis test suggests that the conversion coated Mg alloy has no obvious hemolysis reaction. The hemolysis ratio (HR) of the samples decreases from 11.34% to 1.86% with the HF treatment, which meets the requirements of biomaterials (HR < 5%). The coculture of 3T3 fibroblasts with Mg alloy results in the adhesion and proliferation of cells on the surface of fluoride-coated samples. All the results show that the MgF2 conversion coating would markedly improve the corrosion resistance and in vitro biocompatibility of Mg-Zn-Zr alloy.


Mg-Zn-Zr Alloy hydrofluoric acid (HF) corrosion resistance in vitro biocompatibility biomaterials 


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Copyright information

© Higher Education Press and Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  • Xin-Yu Ye
    • 1
  • Min-Fang Chen
    • 1
    Email author
  • Chen You
    • 1
    • 2
  • De-Bao Liu
    • 1
    • 3
  1. 1.School of Materials Science and EngineeringTianjin University of TechnologyTianjinChina
  2. 2.Tianjin Key Laboratory of Photoelectric Materials and DevicesTianjin University of TechnologyTianjinChina
  3. 3.Key Laboratory of Display Materials and Photoelectric Device (Ministry of Education)Tianjin University of TechnologyTianjinChina

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