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Development of silver nanoparticles-loaded CMC hydrogel using bamboo as a raw material for special medical applications

  • Harish Kumar
  • Ankur GaurEmail author
  • Sushil Kumar
  • Jin-Won Park
Original Paper
  • 19 Downloads

Abstract

The present investigation focuses on the synthesis of silver nanoparticles (Ag-NPs)-loaded hydrogel from synthetic and lab-made carboxymethyl cellulose (CMC) using bamboo as a raw material. The Ag-NPs were made by in situ process by the reaction of CMC and epichlorohydrin in alkaline medium containing silver nitrate. CMC acts as a stabilizer and reducing agent in the formation of nanoparticles. The formation of Ag-NPs was confirmed by UV–Vis spectrophotometer, as an absorption peak around 425 nm was observed. The Ag-NPs antibacterial activity against Escherichia coli (ATCC 433), Bacillus subtilis (ATCC 1688) was calculated by agar disk diffusion technique method. The characterization of the Ag-NPs was done by FTIR, SEM, TEM, particle size analyzer and EDX. Ag-NPs obtained from lab-made CMC displayed a higher antibacterial action towards Gram-negative (Escherichia coli) bacteria as well as Gram-Positive bacteria (Bacillus subtilis) as compared to synthetic CMC obtained from market.

Keywords

Carboxymethyl cellulose Silver nanoparticles (Ag-NPs) Silver nitrate Antibacterial activity Hydrogel 

Notes

Acknowledgements

We greatly acknowledge the support of CIR, MNNIT Allahabad and department of physics, Allahabad University for permitting us to use analytical instruments.

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Copyright information

© Institute of Chemistry, Slovak Academy of Sciences 2018

Authors and Affiliations

  • Harish Kumar
    • 1
  • Ankur Gaur
    • 1
    Email author
  • Sushil Kumar
    • 1
  • Jin-Won Park
    • 2
  1. 1.Department of Chemical EngineeringMotilal Nehru National Institute of TechnologyAllahabadIndia
  2. 2.Department of Chemical and Biomolecular EngineeringYonsei UniversitySeoulRepublic of Korea

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