Chemical Papers

, Volume 71, Issue 11, pp 2159–2166 | Cite as

A simple procedure for the synthesis of novel 3-(benzofur-2-yl)pyrazole-based heterocycles

Original Paper
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Abstract

3-(Benzofuran-2-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde was used, as a precursor for the synthesis of a series of novel heterocycles by facile reactions with 3-oxo-3-phenylpropanenitrile, 2-cyanoethanethioamide, and various hydrazides such as cyanoacetohydrazide, acetohydrazide, and carbohydrazide derivatives. The structures of the products were confirmed by various spectroscopic methods along with the X-ray crystal structures.

Graphical Abstract

Keywords

2-Substituted benzofuran Pyrazole-4-carbaldehyde Carbohydrazide Heterocycles Synthesis 

Notes

Acknowledgements

The project was supported by King Saud University, Deanship of Scientific Research, Research Chairs.

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Copyright information

© Institute of Chemistry, Slovak Academy of Sciences 2017

Authors and Affiliations

  1. 1.Department of Chemistry, College of Science and HumanitiesShaqra UniversityDuwadimiSaudi Arabia
  2. 2.Applied Organic Chemistry DepartmentNational Research CentreGizaEgypt
  3. 3.Cornea Research Chair, Department of Optometry, College of Applied Medical SciencesKing Saud UniversityRiyadhSaudi Arabia

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