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The First Study Evaluating Effectiveness and Safety of the Endoscopic Sleeve Gastroplasty in HIV Patients

  • Thiago Ferreira de Souza
  • Antonio C. Madruga Neto
  • Martin Andres Coronel
  • Eduardo Grecco
  • Luiz Gustavo Quadros
  • Marco SilvaEmail author
  • Barham K Abu Dayyeh
  • Manoel dos Passos Galvão Neto
Brief Communication
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Abstract

The authors evaluated, retrospectively, the endoscopic sleeve gastroplasty impact in seven HIV patients, regarding effectiveness and safety outcomes. The mean baseline body mass index (BMI) was 33.76 kg/m2. The mean baseline CD4+ cell count was 690.43 cells/mm3, and the baseline viral load was undetectable. After 6 months, absolute weight loss, percentage of excess weight loss, percentage total weight loss, and BMI reduction were 20.2 ± 2.6 kg, 85.5 ± 11.1%, 21.3 ± 2.4%, and 7.1 ± 0.8 kg/m2, respectively. No patients presented severe adverse events. After 6 months, the viral load remained undetectable and the mean CD4+ cell count was 710.57 cells/mm3. The endoscopic sleeve gastroplasty is an effective and safe procedure to perform in obese HIV patients.

Keywords

Obesity Gastroplasty Endoscopy Endoscopic therapy HIV AIDS Infectiology 

Notes

Compliance with Ethical Standards

All procedures performed were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Patients have signed the informed consent form.

Conflict of Interest

Marco Silva has no conflict of interest to declare. Also Luiz Gustavo de Quadros is a consultant of Apollo Endosurger.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2020

Authors and Affiliations

  • Thiago Ferreira de Souza
    • 1
  • Antonio C. Madruga Neto
    • 2
  • Martin Andres Coronel
    • 2
  • Eduardo Grecco
    • 1
  • Luiz Gustavo Quadros
    • 1
  • Marco Silva
    • 3
    Email author
  • Barham K Abu Dayyeh
    • 4
  • Manoel dos Passos Galvão Neto
    • 1
  1. 1.ABC Medical SchoolSanto AndréBrazil
  2. 2.Gastrointestinal Endoscopy Unit, Hospital das ClínicasUniversity of São Paulo Medical SchoolSão PauloBrazil
  3. 3.Gastroenterology Department, Centro Hospitalar de São JoãoPorto Medical School – PortoPortoPortugal
  4. 4.Division of Gastroenterology and Hepatology, Mayo ClinicRochesterUSA

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