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Changes in Left Ventricular Mechanics After Sleeve Gastrectomy

  • Eduardo Cavalcanti Lapa SantosEmail author
  • J. M. del Castillo
  • G. B. O. Parente
  • R. P. Pedrosa
  • P. S. Gadelha
  • R. D. Lopes
  • F. Kreimer
  • F. R. M. Neto
Original Contributions
  • 33 Downloads

Abstract

Objective

The aim of this study was to examine echocardiographic parameters of left ventricle (LV) mechanics in obese patients before and after sleeve gastrectomy (SG).

Design and Methods

Twenty-five obese individuals submitted to laparoscopic SG were enrolled in this study. Echocardiography was performed before and after the procedure, and left ventricle mechanics were evaluated by speckle tracking imaging.

Results

Before surgery, altered global longitudinal strain (GLS) values were present in 56% of the patients. In a mean follow-up of 3.6 ± 0.5 months after surgery, there was an increase in GLS values (from 17.4 ± 3.2 to 19.3 ± 2.7%, P = 0.01). There was an inverse correlation between the absolute values of GLS in the preoperative period and the variation in the GLS at follow-up (r = 0.577, P = 0.002). Measurements of global circumferential strain (GCS), global radial strain (GRS), and LV twist were normal preoperatively and did not change after surgery.

Conclusions

Altered global longitudinal strain values were common in young obese patients. Sleeve gastrectomy increased global longitudinal strain even in the early postoperative phase without promoting changes in global radial strain, global circumferential strain, and left ventricle twist measurements.

Keywords

Sleeve gastrectomy Obesity Myocardial strain Cardiac deformation Speckle tracking 

Abbreviations

A

Late diastole

BMI

Body mass index

BP

Blood pressure

E

Early diastole

GCS

Global circumferential strain

GLS

Global longitudinal strain

GRS

Global radial strain

LV

Left ventricle

LVEDV

LV end-diastolic volume

LVEF

LV ejection fraction

LVESV

LV end-systolic volume

PEF

Passive emptying fraction

SG

Sleeve gastrectomy

ST

Speckle tracking

Notes

Authors’ contributions

E. C. L. Santos: study design, data collection, and analysis and manuscript draft

J. M. del Castillo: data collection

G. B. O. Parente: data collection

R. P. Pedrosa: data analysis and manuscript draft

P. S. Gadelha: data analysis and manuscript draft

R. D. Lopes: manuscript draft

F. Kreimer: data collection and manuscript draft

F.R. M. Neto: study design, data collection, and analysis and manuscript draft

Compliance with Ethical Standards

The local ethics committee approved the study. Informed consent was obtained from all individual participants included in the study.

Conflict of Interest

R. D. Lopes reports grants from Amgen, grants from Bristol-Myers Squibb, grants from GlaxoSmithKline, grants from Pfizer, grants from Sanofi-Aventis, personal fees from Bayer, personal fees from Boehringer Ingelheim, from Bristol-Muers Squibb, personal fees from GlaxoSmithKline, personal fees from Pfizer, personal fees from Portola, outside the submitted work. Other authors declare that they have no conflict of interest.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Hospital das Clínicas da Universidade Federal de Pernambuco (UFPE)RecifeBrazil
  2. 2.Pronto Socorro Cardiológico de Pernambuco (PROCAPE)Universidade de PernambucoRecifeBrazil
  3. 3.Realcor, Real Hospital PortuguêsRecifeBrazil
  4. 4.Duke Clinical Research InstituteDurhamUSA

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