Changes in Left Ventricular Mechanics After Sleeve Gastrectomy
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The aim of this study was to examine echocardiographic parameters of left ventricle (LV) mechanics in obese patients before and after sleeve gastrectomy (SG).
Design and Methods
Twenty-five obese individuals submitted to laparoscopic SG were enrolled in this study. Echocardiography was performed before and after the procedure, and left ventricle mechanics were evaluated by speckle tracking imaging.
Before surgery, altered global longitudinal strain (GLS) values were present in 56% of the patients. In a mean follow-up of 3.6 ± 0.5 months after surgery, there was an increase in GLS values (from 17.4 ± 3.2 to 19.3 ± 2.7%, P = 0.01). There was an inverse correlation between the absolute values of GLS in the preoperative period and the variation in the GLS at follow-up (r = 0.577, P = 0.002). Measurements of global circumferential strain (GCS), global radial strain (GRS), and LV twist were normal preoperatively and did not change after surgery.
Altered global longitudinal strain values were common in young obese patients. Sleeve gastrectomy increased global longitudinal strain even in the early postoperative phase without promoting changes in global radial strain, global circumferential strain, and left ventricle twist measurements.
KeywordsSleeve gastrectomy Obesity Myocardial strain Cardiac deformation Speckle tracking
Body mass index
Global circumferential strain
Global longitudinal strain
Global radial strain
LV end-diastolic volume
LV ejection fraction
LV end-systolic volume
Passive emptying fraction
E. C. L. Santos: study design, data collection, and analysis and manuscript draft
J. M. del Castillo: data collection
G. B. O. Parente: data collection
R. P. Pedrosa: data analysis and manuscript draft
P. S. Gadelha: data analysis and manuscript draft
R. D. Lopes: manuscript draft
F. Kreimer: data collection and manuscript draft
F.R. M. Neto: study design, data collection, and analysis and manuscript draft
Compliance with Ethical Standards
The local ethics committee approved the study. Informed consent was obtained from all individual participants included in the study.
Conflict of Interest
R. D. Lopes reports grants from Amgen, grants from Bristol-Myers Squibb, grants from GlaxoSmithKline, grants from Pfizer, grants from Sanofi-Aventis, personal fees from Bayer, personal fees from Boehringer Ingelheim, from Bristol-Muers Squibb, personal fees from GlaxoSmithKline, personal fees from Pfizer, personal fees from Portola, outside the submitted work. Other authors declare that they have no conflict of interest.
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