Obesity Surgery

, Volume 29, Issue 8, pp 2660–2669 | Cite as

Esophagogastric Neoplasms Following Bariatric Surgery: an Updated Systematic Review

  • Mario MusellaEmail author
  • Giovanna Berardi
  • Alessio Bocchetti
  • Roberta Green
  • Valeria Cantoni
  • Nunzio Velotti
  • Katia Di Lauro
  • Domenico Manzolillo
  • Antonio Vitiello
  • Marco Milone
  • Giovanni Domenico De Palma
Review Article


The risk of gastric and/or esophageal cancers after bariatric surgery has been previously discussed in literature. A systematic review was performed to identify articles published between June 2012 and December 2018 reporting new cases of esophageal or gastric cancer not included in previous systematic reviews. Ten gastric malignancies, 28 esophageal cancers, and 2 gastro-intestinal stromal tumors (GIST) were identified. Primary bariatric surgery was a restrictive procedure in 26 cases, a purely malabsorptive procedure in 1 subject, and a gastric bypass in 13 patients. Although the vast majority of bariatric procedures seem to present a negligible relationship with any esophagogastric (EG) malignancy, published data remain incomplete. It was however considered of interest to update the number of EG neoplasms arisen following bariatric surgery.


Mini-bypass One-anastomosis gastric bypass Esophageal cancer Gastric cancer Bariatric surgery 


Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Ethical Approval Statement

This article does not contain any study with human participants or animals performed by any of the authors.

Informed Consent Statement

Does not apply.

Supplementary material

11695_2019_3951_MOESM1_ESM.doc (66 kb)
ESM 1 (DOC 65 kb)
11695_2019_3951_MOESM2_ESM.docx (20 kb)
ESM 2 (DOCX 20 kb)
11695_2019_3951_MOESM3_ESM.docx (18 kb)
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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Mario Musella
    • 1
    Email author
  • Giovanna Berardi
    • 1
  • Alessio Bocchetti
    • 1
  • Roberta Green
    • 1
  • Valeria Cantoni
    • 1
  • Nunzio Velotti
    • 1
  • Katia Di Lauro
    • 1
  • Domenico Manzolillo
    • 1
  • Antonio Vitiello
    • 1
  • Marco Milone
    • 2
  • Giovanni Domenico De Palma
    • 2
  1. 1.Advanced Biomedical Sciences DepartmentFederico II UniversityNaplesItaly
  2. 2.Clinical Medicine and Surgery DepartmentFederico II UniversityNaplesItaly

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