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Current Controversies in Metabolic Surgery for Nonalcoholic Fatty Liver Disease

  • Iraklis Perysinakis
  • Harilaos C. Pappis
  • Elias Margaris
Review Article
  • 41 Downloads

Abstract

Nonalcoholic fatty liver disease (NAFLD) represents the most common liver disease, and it is expected to become the leading cause of end-stage liver disease in the near future. Bariatric operations have beneficial effects on NAFLD, inducing histological resolution of liver damage through weight loss-dependent and weight loss-independent mechanisms. Due to lack of randomized controlled trials, no specific guidelines have been established so far. Yet there is growing evidence that NAFLD will eventually become a formal indication for metabolic surgery. Data regarding the choice of procedure are conflicting, although gastric bypass seems to be slightly superior to sleeve gastrectomy. The purpose of this review is to provide an update on the ongoing research regarding the role of metabolic surgery in NAFLD management.

Keywords

Nonalcoholic fatty liver disease Liver steatosis Steatohepatitis Bariatric surgery Metabolic surgery Gastric bypass Sleeve gastrectomy 

Notes

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Ethical Statement

This article does not contain any studies with human participants or animals performed by authors.

Consent Statement

For this type of study, formal consent is not required.

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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Bariatric and Metabolic Surgery“HYGEIA” HospitalAthensGreece
  2. 2.Third Surgical Department“George Gennimatas” General HospitalAthensGreece

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