Advertisement

Obesity Surgery

, Volume 29, Issue 1, pp 277–280 | Cite as

The Relationship Between Histopathologic Findings and Body Mass Index in Sleeve Gastrectomy Materials

  • Yasemen AdalıEmail author
  • Kenan Binnetoğlu
  • Hüseyin Avni Eroğlu
  • Nilhan Kaya
  • Gülname Fındık Güvendi
Original Contributions
  • 63 Downloads

Abstract

Objective

For treatment of obesity, which is one of the important health problems of the present time, lifestyle modification, pharmacotherapy, behavioral treatment methods, and surgical procedures are commonly used. Sleeve gastrectomy is widely used among surgical procedures. We aimed to investigate the relationship between histopathologic findings and body mass indices (BMIs) of cases with sleeve gastrectomy in our study.

Methods

Thirty-seven patients were included in our study who underwent sleeve gastrectomy and whose operation materials were examined histopathologically in our hospital. Two pathologists re-evaluated all gastrectomy materials. The relationship between BMI and the presence of gastritis, atrophy, intestinal metaplasia (IM), Helicobacter pylori (HPL), and other histopathological findings was investigated.

Results

The mean age of patients included in the study was 34.7 + 9.3 years. Of patients, 70.3% were female and 29.7% were male. There was a statistically significant difference between BMI and IM among the evaluated histopathologic parameters. Moreover, IM was significantly more present in patients with type 2 diabetes.

Conclusions

There is no previous study investigating the relationship between gastric histopathological findings and BMI in sleeve gastrectomy patients. We think that the statistically significant difference between BMI and IM that we found in our study may shed light on studies to be performed in the future.

Keywords

Sleeve gastrectomy Obesity BMI Histopathology Intestinal metaplasia 

Notes

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Ethical Approval

This study was approved by the ethics committee of the Faculty of Medicine of Kafkas University on September 27, 2017 (Document No. 80576354-50-99 / 149).

Informed Consent

For this type of study (retrospective), formal consent is not required.

References

  1. 1.
    Flegal KM, Carroll MD, Ogden CL, et al. Prevalence and trends in obesity among US adults, 1999-2000. JAMA. 2002;288(14):1723–7.CrossRefGoogle Scholar
  2. 2.
    Ogden CL, Carroll MD, Curtin LR, et al. Prevalence of overweight and obesity in the United States, 1999-2004. JAMA. 2006;295(13):1549–55.CrossRefGoogle Scholar
  3. 3.
    Villarejo C, Fernández-Aranda F, Jiménez-Murcia S, et al. Lifetime obesity in patients with eating disorders: increasing prevalence, clinical and personality correlates. Eur Eat Disord Rev. 2012;20(3):250–4.  https://doi.org/10.1002/erv.2166.CrossRefGoogle Scholar
  4. 4.
    Bozbora A. Morbid Obezite. Güncel Cerrahi Tedavi, Çev. Edi. Ergüney S, Çiçek Y, Avrupa Tıp Kitapçılık, İstanbul, 6.Baskı 2001:105–109.Google Scholar
  5. 5.
    World Health Organization. Global health risks: mortality and burden of disease attributable to selected major risks. Geneva: World Health Organization; 2009.Google Scholar
  6. 6.
    Schirmer B, Schauer PR. The surgical management of obesity. In: Brunicardi F, Andersen D, Hunter J, et al., editors. Schwartz’s principles of surgery in the dition. USA: McGraw-Hill Companies; 2010. p. 952–3.Google Scholar
  7. 7.
    Vardar E, Öztürk AM, Ersöz D, et al. Routine careful histopathological examination should be performed in sleeve gastrectomy specimens. J HealthSciences. 2017;7(1):44–9.Google Scholar
  8. 8.
    Safaan T, Bashah M, El Ansari W, et al. Histopathological changes in laparoscopic sleeve gastrectomy specimens: prevalence, risk factors, and value of routine histopathologic examination. Obes Surg. 2017 Jul;27(7):1741–9.  https://doi.org/10.1007/s11695-016-2525-1.CrossRefGoogle Scholar
  9. 9.
    Onzi TR, d’Acampora AJ, de Araújo FM, et al. Gastric histopathology in laparoscopic sleeve gastrectomy: pre- and post-operative comparison. Obes Surg. 2014;24(3):371–6.  https://doi.org/10.1007/s11695-013-1107-8.CrossRefGoogle Scholar
  10. 10.
    Vrabie CD, Cojocaru M, Waller M, et al. The main histopathological gastric lesions in obese patients who underwent sleeve gastrectomy. Dicle Tıp Dergisi / Dicle Medical Journal Cilt. 2010;37(2):97–103. 9Google Scholar
  11. 11.
    Kinsinger LA, Garber JC, Whipple O. A review of sleeve gastrectomy specimen histopathology. Am Surg. 2016;82(11):1101–4.Google Scholar
  12. 12.
    Lauti M, Gormack SE, Thomas JM, et al. What does the excised stomach from sleeve gastrectomy tell us? Obes Surg. 2016;26(4):839–42.  https://doi.org/10.1007/s11695-015-1832-2.11.CrossRefGoogle Scholar
  13. 13.
    Almazeedi S, Al-Sabah S, Al-Mulla A, et al. Gastric histopathologies in patients undergoing laparoscopic sleeve gastrectomies. Obes Surg. 2013;23(3):314–9.  https://doi.org/10.1007/s11695-012-0821-y.CrossRefGoogle Scholar
  14. 14.
    Rath-Wolfson L, Varona R, Bubis G, et al. Gastritis in patients undergoing sleeve gastrectomy: prevalence, ethnic distribution, and impact on glycemic. Medicine (Baltimore). 2017;96(16):e6602.  https://doi.org/10.1097/MD.0000000000006602.CrossRefGoogle Scholar
  15. 15.
    Obeidat FW, Shahait AD, Shanti HA, et al. Histopathology results of Jordanian patients after laparoscopic sleeve gastrectomy. Saudi J Obesity. 2015;3:18–20.CrossRefGoogle Scholar
  16. 16.
    Makki AM, Aldaqal SM, Alorabi SH, et al. Chronic gastritis in morbidly obese patients with sleeve gastrectomy. Electron Physician. 2016;8(1):1786–90.  https://doi.org/10.19082/1786.CrossRefGoogle Scholar
  17. 17.
    Muruzábal FJ, Frühbeck G, Gómez-Ambrosi J, et al. Immunocytochemical detection of leptin in non-mammalian vertebrate stomach. Gen Comp Endocrinol. 2002;128(2):149–52.CrossRefGoogle Scholar
  18. 18.
    Frühbeck G, Gómez-Ambrosi J. Rationale for the existence of additional adipostatic hormones. FASEB J. 2001;15(11):1996–2006.CrossRefGoogle Scholar
  19. 19.
    Moreno-Navarrete JM, Ortega F, Serino M, et al. Circulating lipopolysaccharide-binding protein (LBP) as a marker of obesity-related insulin resistance. Int J Obes. 2012;36(11):1442–9.  https://doi.org/10.1038/ijo.2011.256.CrossRefGoogle Scholar
  20. 20.
    Frühbeck G. Bariatric and metabolic surgery: a shift in eligibility and success criteria. Nat Rev Endocrinol. 2015;11(8):465–77.  https://doi.org/10.1038/nrendo.2015.84. Epub 2015 Jun 9CrossRefGoogle Scholar
  21. 21.
    Martín M, Burrell MA, Gómez-Ambrosi J, et al. Short- and long-term changes in gastric morphology and histopathology following sleeve gastrectomy in diet-induced obese rats. Obes Surg. 2012;22(4):634–40.  https://doi.org/10.1007/s11695-012-0606-3.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of PathologyÇanakkale Onsekiz Mart University Faculty of MedicineÇanakkaleTurkey
  2. 2.Department of General SurgeryKafkas University Faculty of MedicineKarsTurkey
  3. 3.Department of PhysiologyÇanakkale Onsekiz Mart University Faculty of MedicineÇanakkaleTurkey
  4. 4.Department of PathologyEskişehir Yunus Emre State HospitalEskişehirTurkey
  5. 5.Department of PathologyRize Recap Tayyip Erdoğan University Faculty of MedicineRizeTurkey

Personalised recommendations