LSG vs MGB-OAGB—3 Year Follow-up Data: a Randomised Control Trial
- 368 Downloads
The objective of this study is to compare 3-year follow-up results of one anastomosis gastric bypass (MGB-OAGB) and laparoscopic sleeve gastrectomy (LSG) in terms of weight loss, complications, resolution of comorbidities and quality of life.
Materials and Methods
A prospective randomised study of results between 100 LSG patients and 101 MGB-OAGB patients was done from 2012 to 2015. The results were compared regarding operative outcomes, percentage of excess weight loss (%EWL), complications, resolution of comorbidities and quality of life (BAROS score) at 3 years follow-up.
Follow-up was achieved in 93 MGB-OAGB vs 92 LSG patients for 3-year period. The average %EWL for MGB-OAGB vs LSG was 66.48 vs 61.15% at the end of 3 years respectively, which was statistically insignificant. Diabetes remission was seen in 89.13% of MGB-OAGB patients and 81.82% of LSG patients. Remission of hypertension was seen in 74% of MGB-OAGB patients and 72.22% of LSG patients. Bariatric analysis reporting and outcome system (BAROS) with comorbidity in LSG patients and MGB-OAGB patients was 6.03 and 6.96 respectively, whereas in patients without comorbidity, BAROS score was 3.86 in LSG group and 4.34 in MGB-OAGB group.
In our study, at 36 months follow up, there was no significant difference between LSG and MGB-OAGB in %EWL and remission of HTN. Type 2 diabetes mellitus (T2DM) remission rates were higher after MGB-OAGB as compared to LSG but the difference was statistically insignificant. MGB-OAGB patients with comorbidities have a better quality of life and BAROS score compared to LSG patients.
KeywordsOne anastomosis gastric bypass (MGB-OAGB) Laparoscopic sleeve gastrectomy (LSG) Bariatric analysis reporting and outcome system (BAROS) Gastro-esophageal reflux disease (GERD) Percentage excess weight loss (%EWL) Percentage actual weight loss (%AWL) Type 2 diabetes mellitus(T2DM) Hypertension (HTN) Randomised control trial (RCT) Roux-En-Y gastric bypass (RYGB) Quality of life (QOL)
We extend our heartfelt gratitude to Dr. Aruna Tantia, Dr. Pramod Sureka, Dr. Ramanuj Mukherjee, Dr. Abhijit Hazra, Dr. Bimalendu Sen, Dr. Debjit Ghosh, Ram Sundar Bhandari, OT staffs, Shampa Ghosh, Jhuma Chowdhury, Sonam Gupta and Hanie Gupta who have worked hard to make this project a success. The staffs of ILS Hospital deserve a special mention for their dedicated support.
Compliance with Ethical Standards
Statement of Human and Animal Rights
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Informed consent was obtained from all individual participants included in the study.
Conflict of Interest
The authors declare that they have no conflict of interest.
- 2.LeeWJ, Huang MT, Wang W et al. Effects of obesity surgery on the metabolic syndrome. Arch Surg 2004;139(10):1088–1092.Google Scholar
- 11.Angrisani L, Santonicola A, Iovino P et al. Bariatric surgery worldwide 2013. Obes Surg 25(10):1822–1832.Google Scholar
- 12.Stroh C, Weiner R, Horbach T, et al. Kompetenznetz Adipositas, Arbeitsgruppe Adipositaschirurgie. New data on quality assurance in bariatric surgery in Germany. Zentralbl Chir. 138:180–8.Google Scholar
- 13.Magouliotis DE, S V, et al. One-anastomosis gastric bypass versus sleeve gastrectomy for morbid obesity: a systematic review and meta-analysis. Obes Surg. 2017; https://doi.org/10.1007/s11695-017-2807-2.
- 19.Quan Y, Huang A, Ye M, et al. Efficacy of laparoscopic mini gastric bypass for obesity and type 2 diabetes mellitus: a systematic review and meta-analysis. Gastroenterol Res Pract. 2015;152852Google Scholar
- 24.Kothari A, Kanojiya R, et al. Comparison between laparoscopic sleeve gastrectomy (LSG) and mini gastric bypass (MGB-OAGB) for remission of type II diabetes mellitus in morbidly obese patients. IJSR Vol 6 Issue. Apr 2017:4.Google Scholar