Bariatric Surgery in Immunocompromised Patients: Outcomes from One Year Follow-up

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Abstract

Background

Recent Research evidences from across the world indicate the usefulness of bariatric surgery in improving the immunological co-morbidities in patients with morbid obesity.

Aim

The aim of the study was to evaluate the outcome from bariatric surgery in patients presenting with diabetes mellitus and or morbid obesity with immunological co-morbidities.

Methods

It was a retrospective cross-sectional study. Study included patients with morbid obesity with immunological co-morbidities, and additional co- morbidity of type 2 diabetes mellitus in about one third of the cases, who had undergone bariatric surgery during the period 2014–2016 at our center. Patient demographics, preoperative data, and follow-up data were collected and analyzed. Patients were followed for assessing the outcome in terms of BMI and dependency on medications to evaluate the effectiveness of the procedure.

Results

The study included 23 patients (52% female and 48% male). Bariatric surgery was effective in all the patients (except one) in weight reduction. Significant reduction in weight and BMI was observed (p < 0.05). The recent follow-up of these patients showed that the mean BMI of the study group decreased significantly, 34.4% patients had attained normal BMI ≤ 25 kg/m2. Three-month follow-up indicated that 55.56% were not dependent on medications. At 1-year follow-up, 94.4% patients were without any dependency on immunosuppressive medications. Complications included a reversal of surgery and a case of mortality.

Conclusion

The results of our study have shown that immune-compromised patients can undergo bariatric surgery with good weight loss results and improvement in co-morbidities.

Keywords

Immunocompromised BMI Bariatric surgery HIV Psoriasis Obesity 

Notes

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Informed Consent

Informed consent was obtained from all individual participants included in the study.

Statement of Human and Animal Rights

This study was performed in accordance with the principles of declaration of Helsinki and was approved by the Institutional ethical committee.

References

  1. 1.
    Romero-Talamás H, Aminian A, Corcelles R, et al. Psoriasis improvement after bariatric surgery. Surg Obes Relat Dis. 2014;10(6):1155–9.CrossRefPubMedGoogle Scholar
  2. 2.
    Debbaneh M, Millsop JW, Bhatia BK, et al. Diet and psoriasis: part I. Impact of weight loss interventions. J Am Acad Dermatol. 2014;71(1):133–40.CrossRefPubMedPubMedCentralGoogle Scholar
  3. 3.
    Klebanoff MJ, Corey KE, Chhatwal J, et al. Bariatric surgery for nonalcoholic steatohepatitis: a clinical and cost-effectiveness analysis. Hepatology. 2017;65(4):1156–64.CrossRefPubMedGoogle Scholar
  4. 4.
    Raquel G-H, Neil P, Mario M, et al. Patton Kristin, and Elli Enrique F. Bariatric Surgical Practice and Patient Care. 2016;11(1):6–10.CrossRefGoogle Scholar
  5. 5.
    Park S, Kim YJ, Choi CY, et al., Bariatric surgery can reduce albuminuria in patients with severe obesity and normal kidney function by reducing systemic inflammation. Obes Surg. 2017.Google Scholar
  6. 6.
    Tsamalaidze L, Elli EF. Bariatric surgery is gaining ground as treatment of obesity after heart transplantation: report of two cases. Obes Surg. 2017;  https://doi.org/10.1007/s11695-017-2908-y.
  7. 7.
    Gagne DJ, Papasavas PK, Dovec EA, et al. Effect of immunosuppression on patients undergoing bariatric surgery. Surg Obes Relat Dis. 2009;5(3):339–45.CrossRefPubMedGoogle Scholar
  8. 8.
    Fazylov R, Soto E, Merola S. Laparoscopic gastric bypass surgery in human immunodeficiency virus-infected patients. Surg Obes Relat Dis. 2007;3:637–9.CrossRefPubMedGoogle Scholar
  9. 9.
    Hossler EW, Maroon MS, Moward CM. Gastric bypass surgery improves psoriasis. J Am Acad Dermatol. 2011;65(1):198–200.CrossRefPubMedGoogle Scholar
  10. 10.
    Sako EY, Famenini S, Wu JJ. Bariatric surgery and psoriasis. J Am Acad Dermatol. 2014;70(4):774–9.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Nobesity CenterColumbia Asia HospitalAhmadabadIndia
  2. 2.Yenepoya Research CentreYenepoya UniversityMangaloreIndia

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