Obesity Surgery

, Volume 28, Issue 9, pp 2783–2788 | Cite as

Magnesium Sulfate Reduced Opioid Consumption in Obese Patients Undergoing Sleeve Gastrectomy: a Prospective, Randomized Clinical Trial

  • Nurcan KizilcikEmail author
  • Ozge Koner
Original Contributions



The purpose of the study was to investigate the effect of magnesium sulfate on pain management for pain after sleeve gastrectomy operation.


A prospective, randomized, placebo-controlled clinical study.


University hospital.


Eighty patients undergoing sleeve gastrectomy.

Measurements and Main Results

Visual analog scale for the evaluation of pain, sedation score, mean arterial pressure, heart rate, and total analgesic consumption was recorded. Serum magnesium levels were determined before the operation, at the end of the operation, and at 24 h. There were no significant differences between the groups with respect to demographics, and sedation scores. Cumulative morphine consumption and pain scores were found to be higher in the control group than the magnesium group.


Perioperative use of magnesium sulfate reduced postoperative pain and opioid consumption in obese patients undergoing sleeve gastrectomy operations.


Postoperative pain Magnesium sulfate Sleeve gastrectomy Bariatric surgery 


Compliance with Ethical Standards

All procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Informed consent was obtained from all individual participants included in the study.

Conflict of Interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Anesthesiology and Reanimation, School of MedicineYeditepe UniversityIstanbulTurkey

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