The First Report about the Laparoscopic Sleeve Gastrectomy-Induced Lactose Intolerance

  • Masood Amini
  • Masood SepehrimaneshEmail author
  • Leila Vafa
  • Seyedeh Leila Poorbaghi
Brief Communication


The impact of laparoscopic sleeve gastrectomy (LSG) on the lactose intolerance (LI) remains unclear. We checked 8 men and 34 women with mean body mass index (BMI) of 43.94 ± 5.89 kg/m2 for LI using hydrogen breath test and clinical examination before LSG and at 3 months postoperation. In addition to appropriate weight loss (34.30 ± 5.51 kg/m2), 1 man and 3 women, who had not LI at starting, were suffered from LI at 3 months postoperation. Among these four patients, the most and least LI was seen in women who had the lowest and highest percentage of excess BMI loss. It seems LSG can induce LI which must be monitored in postoperative follow-ups.


Bariatric surgery Lactose intolerance Weight loss Secondary hypolactasia 


Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Informed Consent

Informed consent was obtained from all patients.

Statement of Human Rights

All procedures performed in this study were in accordance with the Ethical Committee of Shiraz University of Medical Sciences and with the 1964 Helsinki declaration.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Laparoscopy Research CenterShiraz University of Medical SciencesShirazIran
  2. 2.Gastrointestinal and Liver Diseases Research CenterGuilan University of Medical SciencesRashtIran
  3. 3.Obesity Prevention and Treatment Research CenterShiraz University of Medical SciencesShirazIran
  4. 4.Gastroenterohepatology Research CenterShiraz University of Medical SciencesShirazIran

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