Contribution of Malabsorption to Weight Loss After Roux-en-Y Gastric Bypass: a Systematic Review
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Roux-en-Y gastric bypass (RYGB) is traditionally classified as a combined restrictive and malabsorptive operation. This notion of the operation influences its technical variations and revisions for patients who do not achieve significant weight loss after this surgery. There is an increasing body of literature suggesting a role for appetite suppression mediated by neuro-hormonal signals after RYGB. The purpose of this paper was to systematically review published English language scientific literature to determine the role of malabsorption towards weight loss achieved with RYGB. This review finds that there is little or no malabsorption of carbohydrates or protein after RYGB but there is some fat malabsorption. Overall, malabsorption makes a little (approximately 11.0% in the early period) overall contribution to weight loss after RYGB.
KeywordsGastric bypass Roux-en-Y-gastric bypass Malabsorption Malabsorptive Absorption Carbohydrate Protein Fat
KM conceived the idea for the topic, performed the review, and wrote most of the manuscript. AS critically reviewed the manuscript. Both authors participated in discussions on the topic and contributed to manuscript writing. Both authors have seen the final version and approved of it.
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The authors declare that they have no conflict of interest.
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