Gastrointestinal Quality of Life Improves Significantly After Sleeve Gastrectomy and Roux-en-Y Gastric Bypass—a Prospective Cross-Sectional Study Within a 2-Year Follow-up
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Morbidly obese patients have lower quality of life (QOL) when compared to the general population. So far, no studies have compared gender and procedural differences in gastrointestinal QOL after sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB).
Patients before and after bariatric surgery completed the gastrointestinal quality of life index (GIQLI), a 36-item questionnaire with five subscores. Differences between SG and RYGB were analyzed, as were gender differences.
Some 186 patients completed the questionnaire, 75 before surgery, 56 within 6 months, and 55 within 24 months after surgery. Total GIQLI score and all subscores were significantly better within 24 months after surgery (80.9 ± 19.2 vs. 109.2 ± 17.7, p < 0.001). The specific gastrointestinal items ‘feeling of fullness’, ‘eating pleasure’, ‘slow speed of eating’, and ‘diarrhea’ were also significantly better after surgery whereas many other gastrointestinal items were not different. Total GIQLI score was significantly higher for SG than for RYGB within 6 months, while there were no significant differences within 24 months after surgery. There were also no significant differences in specific gastrointestinal items between SG and RYGB within 24 months after surgery and in total GIQLI score between female and male patients.
Total GIQLI score and all subscores were higher within 24 months after bariatric surgery. Total GIQLI score was significantly higher after SG when compared to RYGB within 6 months, but not different within 24 months after surgery. There was no difference in total GIQLI score between female and male patients.
KeywordsGastrointestinal symptoms Quality of life Gastric sleeve Roux-Y gastric bypass Bariatric surgery Obesity
Body mass index
Diabetes mellitus type II
Excess weight loss
Gastroesophageal reflux disease
Gastrointestinal quality of life index
Quality of life
Randomized controlled trial
Roux-Y gastric bypass
We would like to thank Mr. Jonathan D. Hendrie for proofreading of the manuscript, and we would like to thank Ms. Marion Link for helping with the organization of the study.
Study conception and design: LF, FN, HGK, BPM; acquisition of data: FN, LS, ATB, HGK, LF; analysis and interpretation of data: LF, FN, ATB, LS, TB; drafting of manuscript: FN, LS; critical revision: LF, TB, HGK, BPM.
Compliance with Ethical Standards
Conflict of Interest
The authors declare that they have no competing interests.
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed Consent Statement
Informed consent was obtained from all individual participants included in the study.