Weight Regain 10 Years After Roux-en-Y Gastric Bypass
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This study aims to investigate weight regain and the associated variables 10 years after Roux-en-Y gastric bypass.
This retrospective study recruited patients submitted to Roux-en-Y gastric bypass (N = 166) for a 10-year follow-up. The following variables were investigated: body mass index (BMI), percentage of excess weight loss (%EWL), weight regain (WR), and percentage of weight regain (%WG). The chi-squared test or Fisher’s exact test compared proportions, and the Mann-Whitney test compared numerical measurements between the groups. Analysis of variance (ANOVA) compared the measurements over time. The significance level was set at 5 %.
The sample had a mean age of 39.59 ± 11.69 years, and females prevailed (71.7 %). In the long-term follow-up, 41 % of the patients had weight regain. Seventy-two months after surgery, excess weight, preoperative BMI, gender, age, nutritional monitoring, and iron deficiency did not explain weight regain. Younger patients had regained significantly more weight 96 (p = 0.008) and 120 months (p = 0.004) after surgery than older patients. Patients who regained weight had ferritin <15 μg/dL 96 months after surgery (p = 0.019).
Patients submitted to Roux-en-Y gastric bypass presented weight regain, which increased over time. Age, iron deficiency, and time since surgery were associated with weight regain in the long-term follow-up.
KeywordsWeight regain Bariatric surgery Gastric bypass
We thank the Pontifical Catholic University of Campinas, SP, Brazil and the Coordination for the Improvement of Higher Education Personnel for the master’s scholarship provided to the Master’s Program in Health Sciences of PUC-Campinas, SP, Brazil.
Compliance with Ethical Standards
Statement of Authorship
DVMF conceived and designed the study, collected and analyzed the data, and wrote the manuscript. VALM helped to conceive the study, supervised the research, and reviewed the manuscript. The authors read and approved the final version of the article.
This project was not sponsored.
Conflict of Interests
The authors declare that they have no conflict of interest.
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.
Does not apply. For this type of study, formal consent is not required.
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