Obesity Surgery

, Volume 26, Issue 10, pp 2516–2522 | Cite as

Monitoring of Liver Function Tests after Roux-en-Y Gastric Bypass: An Examination of Evidence Base

  • Kamal K. MahawarEmail author
  • Chetan Parmar
  • Yitka Graham
  • Nimantha De Alwis
  • William R. J. Carr
  • Neil Jennings
  • Peter K. Small
Review Article


There is no consensus on the monitoring of liver function tests after Roux-en-Y gastric bypass (RYGB). Since the main objective of such monitoring would be to diagnose early those who will eventually develop liver failure after RYGB, we performed a systematic review on this topic. An extensive search of literature revealed only 10 such cases in 6 published articles. It would hence appear that liver failure is a rare problem after RYGB. Routine lifelong monitoring of liver function tests is therefore unnecessary for otherwise asymptomatic individuals. Such monitoring should hence be reserved for high-risk groups, such as patients with liver cirrhosis, those undergoing extended limb/distal RYGB, patients with new illnesses, those abusing alcohol, those on hepatotoxic drugs and those presenting with a surgical complication.


Gastric bypass Roux-en-Y gastric bypass Liver function tests Liver failure Liver decompensation Follow-up 



Non-alcoholic fatty liver disease


Non-alcoholic steato-hepatitis


Liver function tests


Roux-en-Y gastric bypass


British Obesity and Metabolic Surgery Society


American Society for Metabolic & Bariatric Surgery


Preferred Reporting Items for Systematic Reviews and Meta-Analyses


Not available


Not otherwise specified


Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflict of interest.

Statement of Human and Animal Rights

Not applicable

Statement of Informed Consent

Not applicable


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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Kamal K. Mahawar
    • 1
    • 2
    Email author
  • Chetan Parmar
    • 1
  • Yitka Graham
    • 1
    • 2
  • Nimantha De Alwis
    • 1
  • William R. J. Carr
    • 1
  • Neil Jennings
    • 1
  • Peter K. Small
    • 1
  1. 1.Bariatric UnitSunderland Royal HospitalSunderlandUK
  2. 2.Department of Pharmacy, Health and Well-beingUniversity of SunderlandSunderlandUK

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