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Goal-Directed Fluid Therapy on Laparoscopic Sleeve Gastrectomy in Morbidly Obese Patients

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Abstract

Background

In bariatric surgery, there are no guidelines available for intraoperative fluid administration. Goal-directed fluid therapy (GDFT) is a new concept of perioperative fluid management that has been shown to improve the prognosis of patients undergoing abdominal surgery. The aim of our study is to assess the impact of the implementation of a GDFT protocol in morbidly obese patients who underwent laparoscopic sleeve gastrectomy (LSG).

Methods

A before-after intervention study, in morbidly obese patients who underwent LSG, was conducted at the Obesity Unit of the General University Hospital Elche. Data from the GDFT implementation group (January 2014 to December 2015) were prospectively collected and compared with a preimplementation group (January 2012 to December 2013).

Results

Baseline demographic and comorbidity data between the two groups of patients were similar. The length of stay in the hospital was significantly shortened in GDFT group from 4.5 to 3.44 days (p < 0.001). Intraoperative fluid administration was significantly lower in the GDFT group (1002.4 vs 1687.2 ml in preimplementation group, p < 0.001). In the postoperative period, there was a statistically significant reduction in postoperative nausea and vomiting (PONV) after GDFT implementation (48 to 14.3 %, p < 0.001).

Conclusions

Implementation of GDFT protocols can prevent intraoperative fluid overload in patients undergoing bariatric surgery. It could improve outcomes, for example decreasing PONV or even hospital stay.

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References

  1. O’Neill T, Allam J. Anesthetic considerations and management of the obese patient presenting for bariatric surgery. Curr Anaesth Crit Care. 2010;21:16–23.

    Article  Google Scholar 

  2. Chappell D, Jecob M, Hofmann-Kiefer K, et al. A rational approach to perioperative fluid management. Anesthesiology. 2008;109(4):723–40.

    Article  PubMed  Google Scholar 

  3. Marik PE, Baram M, Vahid B. Does central venous pressure predict fluid responsiveness? A systematic review of the literature and the tale of seven mares. Chest. 2008;134(1):172–8.

    Article  PubMed  Google Scholar 

  4. Osman D, Ridel C, Ray P, et al. Cardiac filling pressures are not appropriate to predict hemodynamic response to volume challenge. Crit Care Med. 2007;35(1):64–8.

    Article  PubMed  Google Scholar 

  5. Hamilton MA, Cecconi M, Rhodes A. A systematic review and meta-analysis on the use of preemptive hemodynamic intervention to improve postoperative outcomes in moderate and high-risk surgical patients. Anesth Analg. 2011;112(6):1392–402.

    Article  PubMed  Google Scholar 

  6. Pearse RM, Harrison DA, MacDonald N, et al. Effect of a perioperative, cardiac output-guided hemodynamic therapy algorithm on outcomes following major gastrointestinal surgery: a randomized clinical trial and systematic review. JAMA. 2014;311(21):2181–90.

    Article  CAS  PubMed  Google Scholar 

  7. Corcoran T, Rhodes JE, Carke S, et al. Perioperative fluid management strategies in major surgery: a stratified meta-analysis. Anesth Analg. 2012;114(3):640–51.

    Article  PubMed  Google Scholar 

  8. Dalfino L, Giglio MT, Puntillo F, et al. Haemodynamic goal-directed therapy and postoperative infections: earlier is better. A systematic review and meta-analysis. Crit Care. 2011;15(3):R154.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Benes J, Giglio M, Brianza N, et al. The effects of goal-directed fluid therapy based on dynamic parameters on post-surgical outcome: a meta-analysis of randomized controlled trials. Crit Care. 2014;18(5):584.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Jain AK, Dutta A. Stroke volume variation as a guide to fluid administration in morbidly obese patients undergoing laparoscopic bariatric surgery. Obes Surg. 2010;20(6):709–15.

    Article  PubMed  Google Scholar 

  11. Wool DB, Lemmens HJM, Brodsky JB, et al. Intraoperative fluid replacement and postoperative creatine phosphokinase levels in laparoscopic bariatric patients. Obes Surg. 2010;20(6):698–01.

    Article  PubMed  Google Scholar 

  12. Marik PE, Cavallazzi R, Vasu T, et al. Dynamic changes in arterial waveform derived variables and fluid responsiveness in mechanically ventilated patients. A systematic review of the literature. Crit Care Med. 2009;37(9):2642–7.

    Article  PubMed  Google Scholar 

  13. Benes J, Chytra I, Altmann P, et al. Intraoperative fluid optimization using stroke volume variation in high risk surgical patients: results of prospective randomized study. Crit Care. 2010;14:R118.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Lansdorp B, Lemson J, vanPutten MJ, et al. Dynamic indices do not predict volume responsiveness in routine clinical practice. Br J Anaesth. 2012;108:395–401.

    Article  CAS  PubMed  Google Scholar 

  15. Michard F. Rational fluid management/dissecting facts from fiction. Br J Anaesth. 2012;108(3):369–71.

    Article  CAS  PubMed  Google Scholar 

  16. Salome CM, King GG, Berend N. Physiology of obesity and effects on lung function. J Appl Physiol. 2010;108(1):206–11.

    Article  PubMed  Google Scholar 

  17. Serpa Neto A, Hemmes SN, Barbas CS, et al. Protective versus conventional ventilation for surgery: a systematic review and individual patient data meta-analysis. Anesthesiology. 2015;123(1):66–78.

    Article  PubMed  Google Scholar 

  18. Fernandez-Bustamante A, Hashimoto S, Serpa Neto A, et al. Perioperative lung protective ventilation in obese patients. BMC Anesthesiol. 2015;15:56.

    Article  PubMed  PubMed Central  Google Scholar 

  19. Starling EH. The Linacre Lecture on the Law of the Heart. London: Longmans, Green & Co; 1918.

    Google Scholar 

  20. Lobo S, Oliveira NE. Clinical review: What are the best hemodynamic targets for noncardiac surgical patients? Crit Care. 2013;17(2):210.

    Article  PubMed  PubMed Central  Google Scholar 

  21. Kuper M, Gold SJ, Callow C, et al. Intraoperative fluid management guided by oesophageal Doppler monitoring. BMJ. 2011;342:d3016.

    Article  PubMed  Google Scholar 

  22. Noblett SE, Snowden CP, Shenton BK, et al. Randomized clinical trial assessing the effect of Doppler-optimized fluid management on outcome after elective colorectal resection. Br J Surg. 2006;93(9):1069–76.

    Article  CAS  PubMed  Google Scholar 

  23. Abbas SM, Hill AG. Systematic review of the literature for the use of oesophageal Doppler monitor for fluid replacement in major abdominal surgery. Anaesthesia. 2008;63(1):44–51.

    Article  CAS  PubMed  Google Scholar 

  24. Cecconi M, Fasano N, Langiano N, et al. Goal-directed haemodynamic therapy during elective total hip arthroplasty under regional anaesthesia. Crit Care. 2011;15(3):R132.

    Article  PubMed  PubMed Central  Google Scholar 

  25. Vincent JL, Pelosi P, Pearse R, et al. Perioperative cardiovascular monitoring of high-risk patients: a consensus of 12. Crit Care. 2015;19:224.

    Article  PubMed  PubMed Central  Google Scholar 

  26. Dubin A, Pozo MO, Casabella CA, et al. Comparison of 6% hydroxyethyl starch 130/0.4 and saline solution for resuscitation of the microcirculation during the early goal-directed therapy of septic patients. J Crit Care. 2010;25(4):659.

    Article  PubMed  Google Scholar 

  27. Ripolles J, Espinosa A, Casans R, et al. Colloids versus crystalloids in objective-guided fluid therapy, systematic review and meta-analysis. Too early or too late to draw conclusions. Braz J Anesthesiol. 2015;65(4):281–91.

    Article  PubMed  Google Scholar 

  28. Yates D, Davies SJ, Milner HE, et al. Crystalloid or colloid for goal-directed fluid therapy in colorectal surgery. Br J Anaesth. 2014;112(2):281–9.

    Article  CAS  PubMed  Google Scholar 

  29. Giglio MT, Marucci M, Testini M, et al. Goal-directed haemodynamic therapy and gastrointestinal complications in major surgery: a meta-analysis of randomized controlled trials. Br J Anaesth. 2009;103(5):637–46.

    Article  CAS  PubMed  Google Scholar 

  30. Gomez-Izquierdo JC, Feldman LS, Carli F, et al. Meta-analysis of the effect of goal-directed therapy on bowel function after abdominal surgery. Br J Surg. 2015;102(6):577–89.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to José Luis Muñoz.

Ethics declarations

The study was approved by the local ethics committee prior to conduction of the study.

Conflict of Interest

All authors declare that they have no conflict of interest.

Informed Consent

Informed consent was obtained from all individual participants included in the study.

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Muñoz, J.L., Gabaldón, T., Miranda, E. et al. Goal-Directed Fluid Therapy on Laparoscopic Sleeve Gastrectomy in Morbidly Obese Patients. OBES SURG 26, 2648–2653 (2016). https://doi.org/10.1007/s11695-016-2145-9

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  • DOI: https://doi.org/10.1007/s11695-016-2145-9

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