Obesity Surgery

, Volume 26, Issue 2, pp 429–442 | Cite as

Laparoscopic Roux-en-Y Gastric Bypass Versus Laparoscopic Sleeve Gastrectomy to Treat Morbid Obesity-Related Comorbidities: a Systematic Review and Meta-analysis

  • Jianfang Li
  • Dandan Lai
  • Dongping Wu
Review Article


Our aim was to compare laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) for treating morbid obesity and its related comorbidities. An electronic literature search was performed from inception to May 2015 and a total of 18,455 patients, enrolled in 62 recent studies, were included in this meta-analysis. Patients receiving LRYGB had a significantly higher percentage of excess weight loss and better resolution of hypertension, dyslipidemia, gastroesophageal reflux disease, and arthritis compared with those receiving LSG. LRYGB and LSG showed similar effects on type 2 diabetes mellitus and sleep apnea.


Meta-analysis Review Roux-en-Y gastric bypass Sleeve gastrectomy Obesity 



No funding supported

Compliance with Ethical Standard

Conflicts of Interest

Jianfang Li, Dandan Lai, and Dongping Wu declare that they have no conflict of interest.

Ethical Approval

This article does not contain any studies with human participants or animals performed by any of the authors.


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  1. 1.Department of Gastrointestinal SurgeryThe First People’s Hospital of XiaoshanHangzhouChina

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