Obesity Surgery

, Volume 26, Issue 1, pp 169–176 | Cite as

The Impact of Bariatric Surgery on Polycystic Ovary Syndrome: a Systematic Review and Meta-analysis

  • Daniel Skubleny
  • Noah J. Switzer
  • Richdeep S. Gill
  • Mark Dykstra
  • Xinzhe Shi
  • Margaret A. Sagle
  • Christopher de Gara
  • Daniel W. Birch
  • Shahzeer Karmali
Review Article

Abstract

Bariatric surgery has been proven to be a successful management strategy for morbid obesity, but limited studies exist on its effect on polycystic ovary syndrome (PCOS). A comprehensive search of electronic databases was completed. Meta-analysis was performed on PCOS, hirsutism, and menstrual irregularity outcomes following bariatric surgery. Thirteen primary studies involving a total of 2130 female patients were identified. The incidence of PCOS preoperatively was 45.6 %, which significantly decreased to 6.8 % (P < 0.001) and 7.1 % (P < 0.0002) at 12-month follow-up and study endpoint, respectively. The incidences of preoperative menstrual irregularity and hirsutism both significantly decreased at 12-month and at study end follow-up. Bariatric surgery effectively attenuates PCOS and its clinical symptomatology including hirsutism and menstrual irregularity in severely obese women.

Keywords

Bariatric surgery Obesity Polycystic ovary syndrome 

Notes

Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no competing interests.

Consent to Participate

For this type of study, formal consent is not required.

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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Daniel Skubleny
    • 1
  • Noah J. Switzer
    • 2
    • 5
  • Richdeep S. Gill
    • 2
    • 3
  • Mark Dykstra
    • 2
  • Xinzhe Shi
    • 3
  • Margaret A. Sagle
    • 4
  • Christopher de Gara
    • 2
    • 3
  • Daniel W. Birch
    • 2
    • 3
  • Shahzeer Karmali
    • 2
    • 3
  1. 1.Faculty of Medicine and DentistryUniversity of AlbertaEdmontonCanada
  2. 2.Department of Surgery, Faculty of Medicine and DentistryUniversity of AlbertaEdmontonCanada
  3. 3.Centre for the Advancement of Minimally Invasive Surgery (CAMIS)Royal Alexandra HospitalEdmontonCanada
  4. 4.Department of Obstetrics and GynecologyUniversity of AlbertaEdmontonCanada
  5. 5.2D, Walter C Mackenzie Health Sciences CentreUniversity of AlbertaEdmontonCanada

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