Obesity Surgery

, Volume 25, Issue 2, pp 354–359 | Cite as

The Use of a Fibrin Glue with a Low Concentration of Thrombin Decreases Seroma Formation in Postbariatric Patients Undergoing Circular Abdominoplasty

  • Vincenzo Pilone
  • Antonio VitielloEmail author
  • Ciro Borriello
  • Stefano Gargiulo
  • Pietro Forestieri
New Concept



The serum collection under the abdominal flap is the most common complication after a lipo-abdominoplasty. The frequency of seroma increases further among obese patients, who have achieved massive weight loss after bariatric surgery. The purpose of this study is to demonstrate the effectiveness of fibrin glues with a low concentration of thrombin in reducing seroma formation after a lipo-abdominoplasty.


Thirty patients, that had achieved a significant weight loss after an intervention of laparoscopic adjustable gastric banding (LAGB), underwent a circular lipo-abdominoplasty at our bariatric surgery department. Patients were divided into two groups of 15 subjects each: group A underwent traditional surgery; in group B, we applied a slow-clotting variant of fibrin glue (ARTISS, Baxter) under the abdominal flap. All subjects were evaluated clinically using an ultrasound device on postoperative day 15. We considered positive for seroma, those cases with a liquid collection greater than 20 cc.


The groups were homogeneous for age, BMI, male/female ratio, and diabetic or smoker patients. The mean hospital stay was significantly longer in group A than in group B. We found eight cases of serum collection >20 cc in group A and only one case in group B. Hematoma, umbilicus necrosis, and surgical site infection occurred in both groups, but overall complication rate was lower in group B.


The use of a fibrin glue with a low concentration of thrombin could be useful during wound closure and may decrease seroma formation in postbariatric patients undergoing lipo-abdominoplasty.


Bariatric surgery Plastic surgery Abdominoplasty Fibrin sealant Seroma Fibrin glue Postbariatric patients Gastric banding Liposuction ARTISS 


Conflict of Interest

Prof. Vincenzo Pilone has no conflict of interest. Dr. Antonio Vitiello has no conflict of interest, Dr. Ciro Borriello has no conflict of interest, Dr. Stefano Gargiulo has no conflict of interest, and Prof. Pietro has no conflict of interest.

Informed Consent Statement

Informed consent was obtained from all individual participants included in the study.

Statement of Human and Animal Rights

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Supplementary material


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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Vincenzo Pilone
    • 1
  • Antonio Vitiello
    • 2
    Email author
  • Ciro Borriello
    • 2
  • Stefano Gargiulo
    • 2
  • Pietro Forestieri
    • 2
  1. 1.Department of Medicine and SurgeryUniversity of SalernoFisciano SalernoItaly
  2. 2.Department of Gastroenterology, Endocrinology and SurgeryUniversity Hospital of Naples “Federico II”NaplesItaly

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