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Obesity Surgery

, Volume 24, Issue 10, pp 1617–1624 | Cite as

A Randomized Clinical Trial of Laparoscopic Roux-en-Y Gastric Bypass and Sleeve Gastrectomy for the Treatment of Morbid Obesity in China: a 5-Year Outcome

  • Yong Zhang
  • Hongzhi Zhao
  • Zhanguo Cao
  • Xiangyu Sun
  • Chen Zhang
  • Wang Cai
  • Rong Liu
  • Sanyuan Hu
  • Mingfang Qin
Original Contributions

Abstract

Background

No randomized comparative trials have presented long-term outcomes for laparoscopic sleeve gastrectomy (LSG) and laparoscopic Roux-en-Y gastric bypass (LRYGB). The present study was designed to compare the efficacy and safety of these two procedures.

Methods

From January 2007 to July 2008, 64 eligible patients were randomly assigned to LSG or LRYGB. During the 5-year follow-up, we compared morbidity rate, body mass index (BMI), percent of excess weight loss (%EWL), Moorehead-Ardelt (M-A) II quality of life, and resolution or improvement rate of obesity-related comorbidities between the groups.

Results

Both groups were matched with respect to age, gender, and BMI. Slightly more major complications were observed in patients undergoing LRYGB (P > 0.05). Weight loss was significantly better with LRYGB except during the first postoperative year. At 5 years, %EWL for LSG and LRYGB was 63.2 ± 24.5 % and 76.2 ± 21.7 % (P = 0.02), respectively. No statistical difference was observed in quality of life between the groups at all intervals (P > 0.05). At the last follow-up, most comorbidities in both groups were resolved or improved, with no difference between the groups (P > 0.05).

Conclusion

LRYGB and LSG are equally safe and effective in quality of life and improvement or resolution of comorbidities, and LRYGB possesses the superiority in terms of weight loss. Further studies are needed to evaluate micronutrient deficiencies of these procedures.

Keywords

Bariatric surgery Laparoscopy Sleeve gastrectomy Gastric bypass Quality of life 

Notes

Conflict of Interest

The authors declare that they have no conflict of interest with the materials presented here.

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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Yong Zhang
    • 1
    • 2
  • Hongzhi Zhao
    • 1
  • Zhanguo Cao
    • 1
  • Xiangyu Sun
    • 1
  • Chen Zhang
    • 1
  • Wang Cai
    • 1
  • Rong Liu
    • 3
  • Sanyuan Hu
    • 4
  • Mingfang Qin
    • 1
  1. 1.Center of Minimally Invasive SurgeryNankai Hospital of Tianjin Medical UniversityTianjinChina
  2. 2.Gastrointestinal surgeryInner Mongolia People’s HospitalHohhotChina
  3. 3.Chinese PLA General HospitalBeijingChina
  4. 4.Qilu Hospital of Shandong UniversityJinanChina

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