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Obesity Surgery

, Volume 22, Issue 6, pp 896–903 | Cite as

500 Intragastric Balloons: What Happens 5 Years Thereafter?

  • Katerina Kotzampassi
  • Vasilis Grosomanidis
  • Pyrros Papakostas
  • Sofia Penna
  • Efthymios Eleftheriadis
Clinical Research

Abstract

Background

The BioEnterics Intragastric Balloon (BIB) has been considered an effective, less invasive method for weight loss, as it provides a permanent sensation of satiety. However, various non-randomized studies suggest BIB is a temporary anti-obesity treatment, which induces only a short-term weight loss. The purpose of this study was to present data of 500 obese who, after BIB-induced weight reduction, were followed up for up to 5 years.

Methods

The BioEnterics BIB was used, and remained for 6 months. At 6, 12, and 24 months post-removal (and yearly thereafter), all subjects were contacted for follow-up.

Results

From 500 patients enrolled, 26 were excluded (treatment protocol interruption); 474 thus remained, having initial body weight of 126.16 ± 28.32 kg, BMI of 43.73 ± 8.39 kg/m2, and excess weight (EW) of 61.35 ± 25.41. At time of removal, 79 (17%) were excluded as having percent excessive weight loss (EWL) of <20%; the remaining 395 had weight loss of 23.91 ± 9.08 kg (18.73%), BMI reduction of 8.34 ± 3.14 kg/m2 (18.82%), and percent EWL of 42.34 ± 19.07. At 6 and 12 months, 387 (98%) and 352 (89%) presented with weight loss of 24.14 ± 8.93 and 16.31 ± 7.41 kg, BMI reduction of 8.41 ± 3.10 and 5.67 ± 2.55 kg/m2, and percent EWL of 42.73 ± 18.87 and 27.71 ± 13.40, respectively. At 12 and 24 months, 187 (53%) and 96 (27%) of 352 continued to have percent EWL of >20. Finally, 195 of 474 who completed the 60-month follow-up presented weight loss of 7.26 ± 5.41 kg, BMI reduction of 2.53 ± 1.85 kg/m2, and percent EWL of 12.97 ± 8.54. At this time, 46 (23%) retained the percent EWL at >20. In general, those who lost 80% of the total weight lost during the first 3 months of treatment succeeded in maintaining a percent EWL of >20 long term after BIB removal: more precisely, this cutoff point was achieved in 83% at the time of removal and in 53%, 27%, and 23% at 12-, 24-, and 60-month follow-up.

Conclusion

BIB seems to be effective for significant weight loss and maintenance for a long period thereafter, under the absolute prerequisite of patient compliance and behavior change from the very early stages of treatment.

Keywords

Intragastric balloon Obesity Morbid obesity Weight loss Excess weight loss Follow-up 

Notes

Conflict of Interest

All contributing authors declare that they have no conflicts of interest.

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Copyright information

© Springer Science + Business Media, LLC 2012

Authors and Affiliations

  • Katerina Kotzampassi
    • 1
  • Vasilis Grosomanidis
    • 1
  • Pyrros Papakostas
    • 1
  • Sofia Penna
    • 1
  • Efthymios Eleftheriadis
    • 1
  1. 1.Department of SurgeryAristotle’s University of ThessalonikiThessalonikiGreece

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