Obesity Surgery

, Volume 20, Issue 11, pp 1501–1508 | Cite as

Obstetrical and Neonatal Outcomes of Pregnancies following Gastric Bypass Surgery: A Retrospective Cohort Study in a French Referral Centre

  • Pietro Santulli
  • Laurent Mandelbrot
  • Enrico Facchiano
  • Chloé Dussaux
  • Pierre-François Ceccaldi
  • Séverine Ledoux
  • Simon Msika
Clinical Research



The objective of this study was to analyze obstetrical and neonatal outcomes following Roux en Y Gastric Bypass procedures (RYGBP).


A retrospective cohort study was conducted in a single French tertiary perinatal care and bariatric center. The study involved 24 pregnancies, following RYGBP (exposed group) and two different control groups (non-exposed groups). A body mass index (BMI)-matched control group included 120 pregnancies matched for age, parity, and pregnancy BMI. A normal BMI control group included 120 pregnancies with normal BMI (18.5–24.9 kg/m2), matched for age and parity. Hospital data were reviewed from all groups in the same 6-year period. Obstetrical and neonatal outcomes after RYGB were compared, separately, to the two different-matched control groups.


The median interval from RYGBP to conception was 26.6 (range: 3–74) months. Rates of perinatal complications did not differ significantly between the RYGBP group and normal BMI and BMI-matched controls groups. The rate of Cesarean section before labor was higher in the RYGBP patients than in the normal BMI control group (25% vs. 9.3% respectively, p = 0.04). Weight gain was lower in the RYGBP patients than normal BMI control group (5.8 kg vs. 13.2 kg respectively, p < 0.0001). Birthweight was also lower in the RYGBP group than those in normal BMI and BMI-matched controls groups (2,948.2 g vs. 3,368.2 g and 3,441.8 g, respectively, p < 0.0001).


RYGBP surgery was associated with reduced birthweight, suggesting a possible role of nutritional growth restriction in pregnancy.


Obesity Bariatric surgery Roux-en-Y gastric bypass Pregnancy Birthweight Malabsorptive operations Restrictive operations 


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Copyright information

© Springer Science + Business Media, LLC 2010

Authors and Affiliations

  • Pietro Santulli
    • 1
    • 4
  • Laurent Mandelbrot
    • 1
    • 2
  • Enrico Facchiano
    • 2
    • 4
  • Chloé Dussaux
    • 1
    • 2
  • Pierre-François Ceccaldi
    • 1
    • 2
  • Séverine Ledoux
    • 2
    • 3
  • Simon Msika
    • 2
    • 4
  1. 1.Department of Obstetrics and GynaecologyAssistance Publique-Hôpitaux de Paris, Louis Mourier HospitalColombesFrance
  2. 2.Paris 7 Diderot UniversityParisFrance
  3. 3.Department of PhysiologyAssistance Publique-Hôpitaux de Paris, Louis Mourier HospitalColombesFrance
  4. 4.Department of SurgeryAssistance Publique-Hôpitaux de Paris, Louis Mourier HospitalColombesFrance

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