Long-Term Results of Gastric Bypass Surgery in Morbidly Obese Type 1 Diabetes Patients
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Long-term effects of bariatric surgery in morbidly obese type 1 patients are unknown. Five to eight-year experience in the case series of type 1 diabetes subjects is presented.
Three poorly controlled type 1 diabetes patients, aged 19, 23, and 28 underwent Roux-en-Y gastric bypass surgery.
Their maximum body weight reduction noted during the follow-up was between 27% and 31% of baseline body weight, insulin requirement decreased from 0.6–0.95 to 0.3–0.83 IU/kg, and absolute reduction in HbA1c was 3–4%. Significant improvement in blood pressure, plasma lipid profile, and microalbuminuria was noted.
RYGB surgery in morbidly obese type 1 diabetes patients leads to a significant and maintained weight loss and results in remarkable improvement in blood glucose control and concomitant disorders. Bariatric surgery should be recommended to significantly obese type 1 diabetes patients as a means of reduction of vascular complications risk.
KeywordsType 1 diabetes Vascular complications Prevention Morbid obesity Gastric bypass
- 1.Colquitt JL, Picot J, Loveman E, et al. Surgery for obesity. Cochrane Database Syst Rev. 2009;15:CD003641.Google Scholar
- 5.Mechanick JI, Kushner RF, Sugerman HJ, et al. American Association of Clinical Endocrinologists; Obesity Society; American Society for Metabolic & Bariatric Surgery. American Association of Clinical Endocrinologists, The Obesity Society, and American Society for Metabolic & Bariatric Surgery medical guidelines for clinical practice for the perioperative nutritional, metabolic, and nonsurgical support of the bariatric surgery patient. Obesity. 2009;17 Suppl 1:S1–70.PubMedGoogle Scholar
- 6.de Boer IH, Kestenbaum B, Rue TC, et al. Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Study Research Group. Insulin therapy, hyperglycemia, and hypertension in type 1 diabetes mellitus. Arch Intern Med. 2008;22:1867–73.CrossRefGoogle Scholar