Obesity Surgery

, Volume 18, Issue 5, pp 549–559 | Cite as

Compensatory Exercise Hyperventilation is Restored in the Morbidly Obese After Bariatric Surgery

  • Gerald S. Zavorsky
  • Do Jun Kim
  • Nicolas V. Christou
Research Article

Abstract

Background

Morbidly obese individuals may have poor compensatory hyperventilation during exercise. The objective was to examine pulmonary gas exchange and the compensatory hyperventilatory response during exercise pre- and post-weight reduction surgery in obese subjects.

Methods

Fifteen patients (age = 39 ± 8 years, body mass index = 47 ± 6 kg/m2), with an excess weight of 69 ± 17 kg, were recruited. Pulmonary function at rest was assessed and arterial-blood gases were sampled at rest and all levels of exercise pre- and 10 ± 3 weeks postsurgery.

Results

There was a loss of excess weight 21 ± 6 kg (p < 0.01). Waist and hip circumference decreased by 13 ± 9 and 8 ± 7 cm, respectively (p < 0.01). Prior to surgery, there was no compensatory hyperventilation between rest and peak exercise as arterial PCO2 (PaCO2) remained unchanged (37± 3 mm Hg). However, postsurgery, there was compensatory hyperventilation as PaCO2 decreased to 33 ± 2 mm Hg at peak exercise (p < 0.01), with no change in peak oxygen consumption (VO2peak in L/min). Multiple linear regression revealed that the restored ventilatory response to exercise was most strongly associated with the reduction in overall fat mass (adjusted r2 = 0.25; p = 0.03). Total weight loss of 21 kg induces adequate compensatory hyperventilation that begins to show at about 50% of VO2peak, resulting in improved gas exchange at moderate to peak exercise intensities.

Conclusion

Improvement in compensatory hyperventilation is most closely related to loss in overall fat mass.

Keywords

Morbid obesity Exercise Cycling Weight loss Bariatric surgery Ventilation Gas exchange 

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Copyright information

© Springer Science + Business Media, LLC 2008

Authors and Affiliations

  • Gerald S. Zavorsky
    • 1
    • 2
  • Do Jun Kim
    • 1
  • Nicolas V. Christou
    • 3
  1. 1.Department of Obstetrics, Gynecology and Women’s Health, School of Medicine, Saint Mary’s Health CenterSaint Louis UniversitySaint LouisUSA
  2. 2.Department of Pharmacological and Physiological Science, School of MedicineSaint Louis UniversitySaint LouisUSA
  3. 3.Department of Surgery, Bariatric ClinicMcGill University Health CenterMontrealCanada

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