Obesity Surgery

, Volume 17, Issue 3, pp 361–364 | Cite as

Dehydroepiandrosterone Behavior and Lipid Profile in Non-Obese Women undergoing Abdominoplasty

  • José Antonio Robles-Cervantes
  • Manuel Espaillat-Pavonessa
  • Lázaro Cárdenas-Camarena
  • Esperanza Martínez-Abundis
  • Manuel González-Ortiz
Article

Background

The aim of this study was to determine any change in dehydroepiandrosterone (DHEA) and lipid profile in non-obese women after abdominoplasty.

Methods

An auto-controlled clinical trial was carried out. 9 women aged 35 to 40 years with BMI 22–25 kg/m2 were studied. Basal lipid profile and DHEA were performed and repeated 1 month postoperatively. Statistical analysis used Wilcoxon signed-ranks test (two-tailed).

Results

Weight of resected specimen was 606.11 ± 143.4 grams. No significant changes were observed in high-density cholesterol (48.0 ± 9.6 vs 48.8 ± 11.0 mg/dl; P = 0.106) or in triglycerides (119.2 ± 50.9 vs 148.4 ± 45.8 mg/dl; P = 0.139). Significant increases were obtained in DHEA (3.69 ± 3.05 vs 11.09 ± 6.3 ng/ml; P < 0.008), low-density cholesterol (LDL) (87.4 ± 23.5 vs 108.5 ± 28.3 mg/dl; P < 0.008 and total cholesterol (155.1 ± 30.6 vs 186.6 ± 33.1 mg/dl; P < 0.008).

Conclusion

Excision of subcutaneous abdominal fat in studies 1 month later increased DHEA, whose role is controversial in visceral fat distribution, and increased LDL cholesterol and total cholesterol, both risk markers for cardiovascular illness.

Key words

Dehydroepiandrosterone abdominoplasty risk markers cardiovascular disease 

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Copyright information

© Springer Science + Business Media B.V. 2007

Authors and Affiliations

  • José Antonio Robles-Cervantes
    • 1
    • 2
    • 3
  • Manuel Espaillat-Pavonessa
    • 2
  • Lázaro Cárdenas-Camarena
    • 2
  • Esperanza Martínez-Abundis
    • 1
  • Manuel González-Ortiz
    • 1
  1. 1.Medical Research Unit in Clinical Epidemiology, Medical Unit of High SpecialtyMexican Institute of Social SecurityGuadalajaraMexico
  2. 2.Reconstructive Surgery Institute, Health MinistryGuadalajaraMexico
  3. 3.GuadalajaraMexico

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