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Comprehensive appraisement of antioxidant potential and phytochemical profile of native botanicals from Turkey

  • Mehmet Emre ErezEmail author
  • Abdullah Dalar
  • Mehmet Fidan
  • Süleyman Mesut Pınar
Original Paper
  • 13 Downloads

Abstract

This study presents the first comprehensive evaluation of antioxidant potential and phytochemical profiling of nine plant taxa utilized in southeastern and eastern parts of Turkey for various medicinal purposes, in order to contribute the scientific database, which was focused on exploring novel candidates of antioxidant agents from natural sources for industry and complementary medicine. Sequential extracts were prepared from plant materials were prepared through treating different solvents (acetone, ethanol, and water) based on polarity index. According to antioxidant assays via hydrogen atom transfer (HAT) and single atom transfer (SET) mechanisms, acetone extracts were found as the efficient antioxidant sources. Chromatographic studies revealed that phenolic compounds (mainly 5-O-Caffeoylquinic acid, luteolin hexoside, quercetin and rutin) were characterized as major hydrophilic phytochemical compounds and fatty acids (princibally linolenic, palmitic, and linoleic acids) were found as the major volatile compounds that dominantly contribute to the pronounced antioxidant capacities. According to the chemical structure, catechol moiety containing plant extracts had superior antioxidant capacity both for HAT and SET mechanisms. Data obtained from this study showed that among native botanicals, Crepis hakkarica, Crepis gemicii, Laserpitium carduchorum and Hedysarum vanaense might serve bioactive antioxidant agents both for industrial and pharmaceutical use.

Keywords

Antioxidants Phenolics Volatiles Catechol moiety 

Notes

Acknowledgements

None of the authors has a commercial interest, financial interest, and/or other relationship with manufacturers of pharmaceuticals, laboratory supplies and/or medical devices or with commercial providers of medical services.

Compliance with ethical standards

Conflict of interest

The authors are grateful to the The Scientific and Technological Research Council of Turkey (TÜBİTAK) for providing financial assistance of the research (Project Number: 115Z098).

Supplementary material

11694_2019_245_MOESM1_ESM.docx (279 kb)
Electronic supplementary material 1 (DOCX 279 kb)

References

  1. 1.
    M.E. Embuscado, J. Funct. Foods. 18, 811–819 (2015)CrossRefGoogle Scholar
  2. 2.
    M. Kozarski, A. Klaus, D. Jakovljevic, N. Todorovic, J. Vunduk, P. Petrović, M. Niksic, M.M. Vrvic, L. Van Griensven, Molecules 20(10), 19489–19525 (2015)CrossRefGoogle Scholar
  3. 3.
    J.K. Willcox, S.L. Ash, G.L. Catignani, Crit. Rev. Food Sci. Nutr. 44(4), 275–295 (2004)CrossRefGoogle Scholar
  4. 4.
    M.S. Brewer, Compr. Rev. Food Sci. F. 10(4), 221–247 (2011)CrossRefGoogle Scholar
  5. 5.
    A. Mokrani, K. Madani, Sep. Purif. Technol. 162, 68–76 (2016)CrossRefGoogle Scholar
  6. 6.
    K. Khan, H. Fatima, M.M. Taqi, M. Zia, B. Mirza, J. Appl. Res. Med. Arom. Plants 2(3), 77–86 (2015)Google Scholar
  7. 7.
    J. Dai, R.J. Mumper, Molecules 15(10), 7313–7352 (2010)CrossRefGoogle Scholar
  8. 8.
    A. Dalar, I. Konczak, Ind. Crops Prod. 44, 383–390 (2013)CrossRefGoogle Scholar
  9. 9.
    T.C.P. Dinis, V.M.C. Madeira, M.L.M. Almeida, Arch. Biochem. Biophys. 315, 161–169 (1994)CrossRefGoogle Scholar
  10. 10.
    M.S. Blois, Nature 26, 1199–1200 (2002)Google Scholar
  11. 11.
    Y. Uzun, A. Dalar, I. Konczak, Pharm. Biol. 55(1), 532–540 (2017)CrossRefGoogle Scholar
  12. 12.
    I. Pinchuk, H. Shoval, Y. Dotan, D. Lichtenberg, Chem. Phys. Lipids. 165(6), 638–647 (2012)CrossRefGoogle Scholar
  13. 13.
    G.L. Chen, S.G. Chen, Y. Xiao, N.L. Fu, Ind. Crops Prod. 111, 430–445 (2018)CrossRefGoogle Scholar
  14. 14.
    S.B. Nimse, D. Pal, RSC Adv. 5(35), 27986–28006 (2015)CrossRefGoogle Scholar
  15. 15.
    L. Boulekbache-Makhlouf, L. Medouni, S. Medouni-Adrar, L. Arkoub, K. Madani, Ind. Crops Prod. 49, 668–674 (2013)CrossRefGoogle Scholar
  16. 16.
    J.L. Willems, M.M. Khamis, W.M. Saeid, R.W. Purves, G. Katselis, N.H. Low, A. El-Aneed, Anal. Chim. Acta. 933, 164–174 (2016)CrossRefGoogle Scholar
  17. 17.
    E.A. Orabi, M.A. Orabi, M.H. Mahross, M. Abdel-Hakim, J. Saudi Chem. Soc. 22(6), 705–714 (2018)CrossRefGoogle Scholar
  18. 18.
    J.S. Wright, E.R. Johnson, G.A. DiLabio, J. Am. Chem. Soc. 123(6), 1173–1183 (2001)CrossRefGoogle Scholar
  19. 19.
    C. Bakirtzi, K. Triantafyllidou, D.P. Makris, J. Appl. Res. Med. Arom. Plants 3(3), 120–127 (2016)Google Scholar
  20. 20.
    M. Naczk, F. Shahidi, J. Chromatogr. A 1054(1–2), 95–111 (2004)CrossRefGoogle Scholar
  21. 21.
    J. Pérez-Jiménez, F. Saura-Calixto, Food Res. Int. 39(7), 791–800 (2006)CrossRefGoogle Scholar
  22. 22.
    Q.D. Do, A.E. Angkawijaya, P.L. Tran-Nguyen, L.H. Huynh, F.E. Soetaredjo, S. Ismadji, Y.H. Ju, J. Food Drug Anal. 22(3), 296–302 (2014)CrossRefGoogle Scholar
  23. 23.
    T.V. Ngo, C.J. Scarlett, M.C. Bowyer, P.D. Ngo, Q.V. Vuong, J. Food Qual. 2017, 9305047 (2017)CrossRefGoogle Scholar
  24. 24.
    M. Pinelo, L. Manzocco, M.J. Nunez, M.C. Nicoli, Food Chem. 88(2), 201–207 (2004)CrossRefGoogle Scholar
  25. 25.
    D. Fraisse, C. Felgines, O. Texier, J.L. Lamaison, Food Nutr. Sci. 2, 181–192 (2011)Google Scholar
  26. 26.
    R. Amorati, G.F. Pedulli, L. Cabrini, L. Zambonin, L. Landi, J. Agric. Food Chem. 54(8), 2932–2937 (2006)CrossRefGoogle Scholar
  27. 27.
    K.D. Croft, Ann. N. Y. Acad. Sci. 854(1), 435–442 (1998)CrossRefGoogle Scholar
  28. 28.
    M. López-Lázaro, Mini Rev. Med. Chem. 9(1), 31–59 (2009)CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Mehmet Emre Erez
    • 1
    Email author
  • Abdullah Dalar
    • 2
  • Mehmet Fidan
    • 3
  • Süleyman Mesut Pınar
    • 4
  1. 1.Department of Molecular Biology, Faculty of ScienceVan Yuzuncu Yil UniversityVanTurkey
  2. 2.Department of Pharmaceutical Botany, Faculty of PharmacyVan Yuzuncu Yil UniversityVanTurkey
  3. 3.Department of Biology, Faculty of Science and ArtsSiirt UniversitySiirtTurkey
  4. 4.Department of Nutrition and DieteticsVocational School of Health Services, Van Yuzuncu Yil UniversityVanTurkey

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