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Journal of Food Measurement and Characterization

, Volume 13, Issue 4, pp 2887–2893 | Cite as

Antidiabetic potential and multi-biological activities of Trachystemon orientalis extracts

  • Burhanettin Sertaç Ayhan
  • Emine YalçınEmail author
  • Kültiğin Çavuşoğlu
  • Ali Acar
Original Paper
  • 52 Downloads

Abstract

Due to the increase in exposure to chemical substances, the investigation of natural compounds with protective effects has become popular. So in this study the antimicrobial, antioxidant, antimutagenic activities and enzyme inhibitory effects of Trachystemon orientalis leaf and stem extracts were investigated. Antimicrobial effect was determined by disc diffusion method and the antimutagenic effect was investigated by Ames/Salmonella/microsomal test. Antioxidant properties of T. orientalis extracts were determined by investigating the phytochemical contents and 2,2-diphenyl-1-picrylhydrazyl (DPPH) removal activity. The antidiabetic activity of the extracts was investigated by α-amylase and α-glucosidase enzyme inhibition. It has been determined that all extracts exhibit antimicrobial activity at different ratios and the highest antimicrobial activity was obtained with a 21 ± 0.4 mm inhibition zone against Escherichia coli. The highest DPPH removal activity of leaf and stem extracts was determined to be 65.1 ± 2.4% and 59.4 ± 2.7%, respectively. In enzyme inhibitory analysis, it was determined that the α-glucosidase inhibitory effect of extracts was higher than the α-amylase inhibition effect. In antimutagenity test, the highest antimutagenic effects of leaf and stem extract were determined as 78.2 ± 1.1% and 67.2 ± 1.5%, respectively. As a result, T. orientalis leaf and stem extracts were determined as a potential natural antimicrobial, antimutagenic and antioxidant source with a moderately high antidiabetic activity.

Keywords

Antimutagenic activity Antioxidant activity Antidiabetic activity T. orientalis 

Abbreviations

ACE

Acarbose equivalent

BHA

Butylated hydroxytoluene

BHT

Butylated hydroxyanisole

DPPH

2,2-diphenyl-1-picrylhydrazyl

GAE

Gallic acide equivalent

QAE

Quillaja equivalent

Notes

Compliance with ethical standards

Conflict of interest

The present study does not constitute endorsement of the product by the authors or any conflict of interest.

Research involving human and animal participants

This article does not contain any studies with human or animal subjects.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Biology, Faculty of Science and ArtUniversity of GiresunGiresunTurkey
  2. 2.Department of Medical Services and Techniques, Vocational School of Health ServicesUniversity of GiresunGiresunTurkey

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