Comparative analysis of antioxidant and antimelanogenesis properties of three local guava (Psidium guajava L.) varieties of Thailand, via different extraction solvents
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Abstract
The antioxidant and antimelanogenesis potentials of three local varieties of guava (Psidium guajava L.) from Thailand namely: Pansithong, Thai original and Kimju were studied. The extracts were made with water, 40 % ethanol and simulated gastrointestinal digestion (SGD). Antioxidant properties were determined by total polyphenolic compounds, DPPH assay, superoxide anion assay and hydroxyl radical assay. Antimelanogenesis properties were determined by anti-tyrosinase assay, total phenolic acid and total vitamin C contents. The results for antioxidant analysis revealed that Pansithong, when extracted by 40 % ethanol and SGD showed the presence of highest polyphenol compounds, and DPPH antioxidant activity respectively. Kimju exhibited the highest hydroxyl radical antioxidant activity among all extracts and highest superoxide anion antioxidant activity, when extracted by 40 % ethanol. The results for antimelanogenesis determination presented that Kimju showed highest tyrosinase inhibition, total phenolic acid and total vitamin C contents. It was concluded that Pansithong showed highest antioxidant potential while the highest antimelanogenesis potential was found in Kimju. Over all water has been found as the best solvent for antioxidant extraction followed by 40 % ethanol and SGD.
Keywords
Antioxidants Antimelanogents Guava Extraction solventsReferences
- 1.R.M. Acheson, D.R.R. Williams, Does consumption of fruit and vegetables protect against stroke? Lancet 321, 1191–1193 (1983)CrossRefGoogle Scholar
- 2.K.A. Steinmetz, J.D. Potter, Vegetable, fruit, and cancer prevention: a review. J Am. Diet. Assoc 2, 325–357 (1991)Google Scholar
- 3.G. Block, B. Patterson, A. Suber, Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence. Nutr. Cancer 18, 1–29 (1992)CrossRefGoogle Scholar
- 4.A.M. Papas, Antioxidant status, diet, nutrition, and health (CRC Press, London, 1999)Google Scholar
- 5.T.P.A. Devasagayam, J.C. Tilak, K.K. Boloor, K.S. Sana, S.S. Ghaskadbi, R.D. Lele, Free radicals and antioxidants in human health: current status and future prospects. JAPI 52, 794–804 (2004)Google Scholar
- 6.H.A. Jung, Antioxidant flavonoids and chlorogenic acid from the leaves of Eriobotrya japonica. Arch. Pharm. Res. 22, 213–218 (1999)CrossRefGoogle Scholar
- 7.G.C. Yen, H.Y. Chem, Antioxidant activity of various tea extracts in relation to their antimutagenicity. J. Agric. Food Chem. 43, 27–32 (1995)CrossRefGoogle Scholar
- 8.P.G. Pietta, Flavonoids as antioxidants. J. Nat. Prod. 63, 1035–1042 (2002)CrossRefGoogle Scholar
- 9.K. Scharffetter-Kochanek, P. Brenneisen, J. Wenk, G. Herrmann, W. Ma, L. Kuhr, C. Meewes, M. Wlaschek, Photoaging of the skin from phenotype to mechanisms. Exp. Gerontol. 35, 307–316 (2000)CrossRefGoogle Scholar
- 10.S.R. Pinnell, Cutaneous photodamage, oxidative stress, and topical antioxidant protection. J. Am. Acad. Dermatol. 48, 1–19 (2003)CrossRefGoogle Scholar
- 11.R. Busca, R. Ballotti, Cyclic AMP a key messenger in the regulation of skin pigmentation. Pigment Cell Res. 13, 60–69 (2000)CrossRefGoogle Scholar
- 12.J.K. No, D.Y. Soung, Y.J. Kim, K.H. Shim, Y.S. Jun, S.H. Rhee, T. Yokozawa, H.Y. Chung, Inhibition of tyrosinase by green tea components. Life Sci. 65, 241–246 (1999)CrossRefGoogle Scholar
- 13.L.S. Cobley, Introduction to Botany of Tropical Crops (Longman, New York, 1956)Google Scholar
- 14.T. Damsud, Antioxidant and anti-melanogenesis properties of guava (Psidium guajava L.) extracts in vitro. Academic Thesis, Chulalongkorn University, Bangkok, Thailand (2008)Google Scholar
- 15.U.L. Yadava, Guava (Psidium guajava L.) an exotic tree fruit with potential in the south eastern United States. Hort. Sci. 31, 789–794 (1996)Google Scholar
- 16.H.T. Le, J.F. Hancock, T.T. Trinh, The fruit crop of Vietnam: introduced species and their native relatives. Fruit Var. J. 52, 158–168 (1998)Google Scholar
- 17.D. Tate, Tropical Fruit of Thailand (Asia Books Co. Ltd., Bangkok, 2000)Google Scholar
- 18.C.W. Wilson III, Guava, in Tropical and Subtropical Fruits, ed. by S. Nagy, P.E. Shaw (The AVI Publishing Company Inc., Westport, 1980), pp. 279–299. (1980)Google Scholar
- 19.R.N. Adsule, S.S. Kadam, Guava, in Hand Book of Fruit Science and Technology: Production, Composition, Storage, and Processing (Marcel Dekker, New York, 1995), pp. 419–433Google Scholar
- 20.H.Y. Nakasone, R.E. Paull, Tropical Fruits (CAB Interational, Wallingford, 1998)Google Scholar
- 21.T.R. Seshadri, K. Vasishta, Polyphenolic compounds of guava fruits. Curr. Sci. 33, 334–335 (1964)Google Scholar
- 22.K. Misra, T.R. Seshadri, Chemical components of the fruit of Psidium guajava. Phytochemistry 7, 641–664 (1968)CrossRefGoogle Scholar
- 23.K.H. Miean, S. Mohamed, Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plants. J. Agric. Food Chem. 49, 3106–3112 (2001)CrossRefGoogle Scholar
- 24.A. Jimenez-Escrig, M. Rincon, R. Pulido, F. Saura-Calixto, Guava fruit (Psidium guajava L.) as a new source of antioxidant dietary fiber. J. Agri. Food Chem. 49, 5489–5493 (2001)CrossRefGoogle Scholar
- 25.L.P. Leong, G. Shi, An investigation of antioxidant capacity of fruits in Singapore markets. Food Chem. 76, 69–75 (2002)CrossRefGoogle Scholar
- 26.C. Guo, J. Yang, J. Wei, Y. Li, J. Xu, Y. Jiang, Antioxidant activities of peel, pulp and seed fractions of common fruits as determined by FRAP assay. Nutr. Res. 23, 1719–1726 (2003)CrossRefGoogle Scholar
- 27.K. Thaipong, U. Boonprakob, L. Cisneros-Zevallos, D.H. Byrne, Hydrophilic and lipophilic antioxidant activities of Guava fruits. Southeast Asian J. Trop. Med. Public Health 36, 254–257 (2005)Google Scholar
- 28.I. Parejo, Comparison between the radical scavenging activity and antioxidant activity of six distilled and non distilled Mediterranean herbs and aromatic plants. J. Agric. Food Chem. 50, 6882–6890 (2002)CrossRefGoogle Scholar
- 29.N. Abe, T. Murata, Hirota, Novel DPPH radical scavengers, bisorbicillinol and demethyltrichodimerol, from fungus. Biosci. Biotecnol. Biochem. 62, 661–666 (1998)CrossRefGoogle Scholar
- 30.P. Valentao, E. Fernandes, F. Carvalho, P.B. Andrade, R.M. Seabra, M.L. Bastos, Antioxidant properties of Cardoon (Cynara cardunculus L.) infusion against superoxide radical, hydroxyl radical, and hypochlorous acid. Agric. Food Chem. 50, 4989–4993 (2002)CrossRefGoogle Scholar
- 31.O. Nerya, R. Musa, S. Khatib, S. Tamir, J. Vaya, Chalcones as potent tyrosinase inhibitors: the effect of hydroxyl positions and numbers. Phytochemistry 65, 1389–1395 (2004)CrossRefGoogle Scholar
- 32.C. Hui-Yin, Y. Gow-Chin, Antioxidant activity and free radical-scavenging capacity of extracts from guava (Psidium guajava L.) leaves. Food Chem. 101, 686–694 (2007)CrossRefGoogle Scholar
- 33.F. Naoto, Rapid high-performance liquid chromatographic identification/quantification of total vitamin C in fruit drinks. Food Control 12, 27–29 (2000)Google Scholar
- 34.M. Naczk, F. Shahidi, Phenolics in cereals, fruits and vegetables: occurrence, extraction and analysis. J. Phar. Biomed. Anal. 41, 1532–1542 (2006)Google Scholar
- 35.N.E. Durling, O.J. Catchpole, J.B. Grey, R.F. Webby, K.A. Mitchell, L.Y. Foo, N.B. Perry, Extraction of phenolics and essential oil from dried sage (Salvia officinalis) using ethanol-water mixtures. Food Chem. 101, 1417–1424 (2007)CrossRefGoogle Scholar
- 36.L. Yan, L.T. Theng, T. Jhi, Antioxidant properties of guava fruit: comparison with some local fruits. Sunway Acad. J. 3, 9–20 (2006)Google Scholar
- 37.K. Mahattanatawee, E.A. Baldwin, Total antioxidant activity and fiber content of select Florida-grown tropical fruits. J. Agric. Food Chem. 54, 7355–7363 (2006)CrossRefGoogle Scholar
- 38.K. Noda, Y. Nishiwaki, M. Kawahara, S. Negoro, T. Sugiura, A. Yokoyama, M. Fukuoka, K. Mori, K. Watanabe, T. Tamura, S. Yamamoto, N. Saijo, Irinotecan plus cisplatin compared with etoposide plus cisplatin for extensive small-cell lung cancer. N. Engl. J. Med. 346, 85–91 (2002)CrossRefGoogle Scholar
- 39.S.N. Lim, P.C.K. Cheung, V.E.C. Ooi, P.O. Ang, Evaluation of antioxidative activity of extracts from a brown seaweed, Sargassum siliquastrum. J. Agric. Food Chem. 50, 3862–3866 (2002)CrossRefGoogle Scholar
- 40.P.M. Abuja, M. Murkovic, W. Pfannhauser, Antioxidant and prooxidant activities of Elderberry (Sambucus nigra) extract in low-density lipoprotein oxidation. J. Agric. Food Chem. 46, 4091–4096 (1998)CrossRefGoogle Scholar
- 41.G. Cao, E. Sofic, R. Prior, Antioxidant and prooxidant behavior of flavonoids: structure-activity relationships. Free Radical Biol. Med. 22, 749–760 (1997)CrossRefGoogle Scholar
- 42.C.F. Yen, M.Y. Chong, M.C. Kuo, C.S. Chang, Severe granulocytopenia secondary to chlorpromazine despite concurrent lithium treatment: a case report. Kaohsiung J. Med. Sci. 10, 635–638 (1997)Google Scholar
- 43.L.N. Grinberg, H. Newmark, N. Kitrossky, E. Rahamin, M. Chevion, E.A. Rachmilewitz, Protective effects of tea polyphenols against oxidative damage to red blood cells. Biochem. Pharmacol. 54, 973–978 (1997)CrossRefGoogle Scholar
- 44.Y. Kubo, J.P. Adelman, D.E. Clapham, L.Y. Jan, A. Karschin, Y. Kurachi, M. Lazdunski, H.A. Lester, C.G. Nichols et al., Kir potassium channels, in The IUPHAR Compendium of Voltage-gated Ion Channels, ed by W.A. Catterall, K.G. Chandy, G. Gutman (IUPHAR Media, Leeds, 2002), pp. 153–172Google Scholar
- 45.F. Vallejo, C. Garcia-Viguera, In vitro gastrointestinal digestion study of Broccoli florescence, phenolic compounds, glucosinolates, and vitamin C. J. Agric. Food Chem. 52, 135–138 (2004)CrossRefGoogle Scholar
- 46.A. Pérez-Vicente, D. Martínez-Romero, A. Carbonell, M. Serrano, F. Riquelme, F. Guillén, D. Valero, Role of polyamines in extending shelf life and the reduction of mechanical damage during plum (Prunus salicina Lindl.) storage. Postharvest Biol. Technol. 25, 25–32 (2002)CrossRefGoogle Scholar
- 47.B.L. Yen, C.J. Chang, K.J. Liu, Y.C. Chen, H.I. Hu, C.H. Bai, M.L. Yen, Brief report—human embryonic stem cell-derived mesenchymal progenitors possess strong immunosuppressive effects toward natural killer cells as well as T lymphocytes. Stem Cells 27, 451–456 (2009)CrossRefGoogle Scholar
- 48.J. Chalas, A. Bella, Effect of ethyl esterification of phenolic acids on low-density lipoprotein oxidation. Biomed. Pharmacother 55, 54–60 (2001)CrossRefGoogle Scholar
- 49.Y.Y. Lim, T.T. Lim, J.J. Tee, Antioxidant properties of several tropical fruits: a comparative study. Food Chem. 103, 1003–1008 (2007)CrossRefGoogle Scholar
- 50.C. Vasco, J. Ruales, A. Kamal-Eldin, Total phenolic compounds and antioxidant capacities of major fruits from Ecuador. Food Chem. 111, 816–823 (2008)CrossRefGoogle Scholar
- 51.M. Alothman, R. Bhat, A.A. Karim, Antioxidant capacity and phenolic content of selected tropical fruits from Malaysia, extracted with different solvents. Food Chem. 115, 785–788 (2009)CrossRefGoogle Scholar
- 52.J. Contreras-Caldeŕon, L. Calderón-Jaimes, E. Guerra-Hernández, B. García-Villanova, Antioxidant capacity, phenolic content and vitamin C in pulp, peel and seed from 24 exotic fruits from Colombia. Food Res. Int. 44, 2047–2053 (2011)CrossRefGoogle Scholar
- 53.L. Fu, B. Xu, X. Xu, R. Gan, Y. Zhang, E. Xia, H. Li, Antioxidant capacities and total phenolic contents of 62 fruits. Food Chem. 129, 345–350 (2011)CrossRefGoogle Scholar
- 54.J. Gull, B. Sultana, F. Anwar, R. Naseer, M. Ashraf, M. Ashrafuzaman, Variation in antioxidant attributes at three ripening stages of Guava (Psidium guajava L.) fruit from different geographical regions of Pakistan. Molecules 17, 3165–3180 (2012)CrossRefGoogle Scholar