Total pancreatic necrosis after organophosphate intoxication
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Cases of acute pancreatitis induced by organophosphate intoxication are encountered occasionally in clinics, but very few of them develop into severe pancreas necrosis and irreversible pancreatic function impairment. Here, we report a 47-year-old female organophosphate poisoning case after ingestion of massive insecticides; she was considered to have total necrosis and function failure of the pancreas via serum amylase test, glucose level test, and CT imaging. The patient exhibited no relief under the regular medicine treatment, which included sandostatin, antibiotics, intravenous atropine, and pralidoxime methiodide. She received percutaneous catheterization and drainage of pancreatic zone to expel hazardous necrotic waste, also by which the pathogenic evidence was obtained and the antibiotics were adjusted subsequently. The patient recovered gradually, was discharged after 2 weeks, and was prescribed with oral pancreatin capsules before meals and hypodermic insulin at meals and bedtime to compensate the impaired pancreatic function.
Keywordsorganophosphate intoxication severe acute pancreatitis pancreas necrosis percutaneous catheterization sandostatin insulin
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We thank Dr. Jingya Zhou from the Department of Medical Records for her kind support in the retrieval of documents.
- 4.Roeyen G, Chapelle T, Jorens P, de Beeck BO, Ysebaert D. Necrotizing pancreatitis due to poisoning with organophosphate pesticides. Acta Gastroenterol Belg 2008; 71(1): 27–29Google Scholar
- 5.Venugopal L, Dharma Rao V, Srinivas Rao M, Mallikarjuna Y. Toxic pancreatitis with an intra-abdominal abscess which was caused by organophosphate poisoning (OP). J Clin Diagn Res 2013; 7(2): 366–368Google Scholar
- 6.Hamaguchi M, Namera A, Tsuda N, Uejima T, Maruyama K, Kanai T, Sakata I. Severe acute pancreatitis caused by organophosphate poisoning. Chudoku Kenkyu 2006; 19(4): 395–399Google Scholar