Frontiers of Medicine

, Volume 11, Issue 1, pp 129–136 | Cite as

A comparative study of electroacupuncture at Zhongliao (BL33) and other acupoints for overactive bladder symptoms

  • Likun Yang
  • Yang Wang
  • Qian Mo
  • Zhishun LiuEmail author
Research Article


Electroacupuncture (EA) at Zhongliao (BL33) can improve the symptoms of overactive bladder (OAB), such as urinary frequency, urgency, and incontinence. However, its performance compared with other acupoints remains unclear. This study investigated the effects of EA at BL33 with deep needling on rats with OAB by detecting urodynamics in eight groups: no intervention group, D-BL33 group (deep needling at BL33), S-BL33 group (shallow needling at BL33), non-acupoint group (needling at the non-acupoint next to BL33), Weizhong (BL40) group, Sanyinjiao (SP6) group, Tongtian (BL7) group, and Hegu (LI4) group. Results revealed that EA at BL33 with deep needling, BL40, and SP6 prolonged the intercontraction interval (ICI) of rats with OAB (P = 0.001, P = 0.005, P = 0.046, respectively, post-treatment vs. post-modeling). Furthermore, the change in ICI from post-modeling in the D-BL33 group was significantly greater than those of the no intervention and other EA groups (all P < 0.01). Significantly shortened vesical micturition time (VMT) and elevated maximum detrusor pressure (MDP) were also observed in the D-BL33 group (P = 0.017 and P = 0.024, respectively, post-treatment vs. post-modeling). However, no statistically significant differences in the changes of VMT and MDP from post-modeling were observed between D-BL33 and the other EA groups. In conclusion, EA at BL33 with deep needling may inhibit acetic-acid-induced OAB more effectively.


overactive bladder electroacupuncture acupuncture points 


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This study was supported by the National Natural Science Foundation of China (Nos. 81173353 and 81373732).


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Copyright information

© Higher Education Press and Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  1. 1.Department of Acupuncture, Guang’anmen HospitalChina Academy of Chinese Medical SciencesBeijingChina
  2. 2.Graduate College of Tianjin University of Traditional Chinese MedicineTianjinChina
  3. 3.School of Acupuncture-Moxibustion and TuinaGuiyang College of Traditional Chinese MedicineGuiyangChina
  4. 4.Department of Acupuncturethe Second Affiliated Hospital of Guiyang College of Traditional Chinese MedicineGuiyangChina

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