Archives of Osteoporosis

, 13:121 | Cite as

Osteoporosis in postmenopausal women in this decade: a bibliometric assessment of current research and future hotspots

  • Yuanyu QiuEmail author
  • Wu Yang
  • Qijin Wang
  • Sijia Yan
  • Bo LiEmail author
  • Xiao ZhaiEmail author
Review Article



Postmenopausal osteoporosis (PMOP) has already become a major public health problem. However, there was no bibliometric analysis estimating the evolutionary process of PMOP research.


This study aimed to assess its scientific activity.


Publications on PMOP were retrieved from Science Citation Index-Expanded (SCI-E) of the Web of Science (WoS) from 2008 to 2018. VOSviewer software was used for data mining and visualization. The quantity of papers, number of citations, citation frequency per year, and H-index were assessed and compared among different countries, institutes, and researchers.


A total of 11,142 papers were included and were cited 184,416 times. The USA contributed the most papers (3162), the most citations (83,270 times), and the highest H-index (115). Canada ranked first for the number of papers per million populations and per trillion GDP. Seven of the top ten funding agencies were industries. The key words were stratified into four clusters: cluster 1 (“basic research”), cluster 2 (“diagnosis”), cluster 3 (“treatment”), and cluster 4 (“others”). Average appearing years (AAY) of key words in cluster 1 were the largest compared to those in clusters 2 and 3. For hotspots, “miRNA” showed a relatively latest AAY of 2017.63, followed by “abaloparatide” and “adipokine”.


We concluded that the USA and Europe were the most productive regions on PMOP, with a high prevalence of articles supported by pharmaceutical companies. Key word focus gradually shifted from “diagnosis” to “treatment” and then to precision medicine orientated “basic research”. It is recommended to pay attention to potential research hotspots, such as “miRNA,” “abaloparatide,” and “adipokine”.


Bibliometric Citation H-index Postmenopausal osteoporosis Hotspots 



postmenopausal osteoporosis


science citation index-expanded


web of science


gross domestic product


impact factor


average appearing years


randomized controlled trial


bone mineral density


fracture risk assessment tool


Authors’ contributions

X, Z and B, L: conceived and designed the experiments. YY, Q, and W, Y: performed the experiments: QJ, W analyzed the data. YY, Q and SJ, Y: wrote the paper. All authors read and approved the final manuscript.


This study was supported by Foundation of Changhai Hospital (CH201717); National Natural Science Foundation of China (81701199).

Compliance with ethical standards

Conflict of interest


Ethical approval and consent to participate

Not applicable.

Consent for publication

Not applicable since the manuscript is entirely original; the tables and figures presented are original for this article and have neither been published nor are currently under consideration for publication by any other journal.

Supplementary material

11657_2018_534_MOESM1_ESM.xls (71 kb)
ESM 1 (XLS 71 kb)
11657_2018_534_MOESM2_ESM.docx (67 kb)
ESM 2 (DOCX 66 kb)


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Copyright information

© International Osteoporosis Foundation and National Osteoporosis Foundation 2018

Authors and Affiliations

  1. 1.Department of Gynecology and ObstetricsThe Affiliated Jiangyin Hospital of Southeast UniversityJiangyinChina
  2. 2.Department of OrthopedicsThe Affiliated Jiangyin Hospital of Southeast UniversityJiangyinChina
  3. 3.Department of Endocrinology, Changhai HospitalSecond Military Medical UniversityShanghaiChina
  4. 4.Department of Orthopedics, Changhai HospitalSecond Military Medical UniversityShanghaiChina

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