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Archives of Osteoporosis

, 13:29 | Cite as

Bone: best papers of the year 2017

  • Michaël R. LaurentEmail author
Review

Abstract

Summary

An overview of selected papers related to bone published in 2017 is provided.

Purpose

This paper accompanies a lecture at the 2018 Belgian Bone Club annual Clinical Update Symposium held in Brussels on January 20th, discussing the best papers (in the opinion of the author) published in the previous year.

Methods

A PubMed search using the keyword “bone” and articles published in 2017.

Results

Hot topics include screening for osteoporosis, novel anabolic drugs such as romosozumab and abaloparatide for osteoporosis and rare metabolic bone diseases, as well as long-term efficacy of denosumab and possible risk of multiple vertebral fractures following its discontinuation. Other selected articles cover effectiveness of bisphosphonates and changes in mineralization after long-term use, new guidelines for glucocorticoid- and aromatase inhibitor-induced osteoporosis, increasing use of high-dose vitamin D supplements despite lack of evidence for their widespread high-dose use, and cardiovascular safety concerns surrounding the use of calcium supplements. Other topics discussed are effects of diabetes on bone health, reciprocal crosstalk between bone cells and adipose tissue, and resistance exercise training to prevent bone loss and sarcopenia.

Conclusions

These papers offer a hopeful outlook for a better treatment and management of patients with osteoporosis and other metabolic bone diseases anno 2018.

Keywords

Osteoporosis Screening Bone anabolic drugs Vertebral fractures Vitamin D Calcium supplements 

Notes

Funding information

No funding was obtained related to this work.

Compliance with ethical standards

Conflicts of interest

MRL is a member of the Board of the Belgian Bone Club and has received consultancy fees from Alexion, Novartis, and Sandoz and lecture fees from Amgen. The opinions in this work represent the sole view of the author and not of the Belgian Bone Club.

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Copyright information

© International Osteoporosis Foundation and National Osteoporosis Foundation 2018

Authors and Affiliations

  1. 1.Centre for Metabolic Bone DiseasesUniversity Hospitals LeuvenLeuvenBelgium

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