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Chinese Journal of Integrative Medicine

, Volume 25, Issue 11, pp 861–866 | Cite as

Analysis on Composition Rules of Chinese Patent Drugs Treating Pain-Related Diseases Based on Data Mining Method

  • Shi-huan Tang
  • Dan Shen
  • Hong-jun YangEmail author
Original Article

Abstract

Objective

To analyze the composition rules of oral prescriptions in the treatment of headache, stomachache and dysmenorrhea recorded in National Standard for Chinese Patent Drugs (NSCPD) enacted by Ministry of Public Health of China and then make comparison between them to better understand pain treatment in different regions of human body.

Methods

Constructed NSCPD database had been constructed in 2014. Prescriptions treating the three pain-related diseases were searched and screened from the database. Then data mining method such as association rules analysis and complex system entropy method integrated in the data mining software Traditional Chinese Medicine Inheritance Support System (TCMISS) were applied to process the data.

Results

Top 25 drugs with high frequency in the treatment of each disease were selected, and 51, 33 and 22 core combinations treating headache, stomachache and dysmenorrhea respectively were mined out as well.

Conclusions

The composition rules of the oral prescriptions for treating headache, stomachache and dysmenorrhea recorded in NSCPD has been summarized. Although there were similarities between them, formula varied according to different locations of pain. It can serve as an evidence and reference for clinical treatment and new drug development.

Keywords

Chinese patent drug headache stomachache dysmenorrhea pain Traditional Chinese Medicine Inheritance Support System formulating principle 

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Notes

Author Contributions

Yang HJ designed the project, Shen D collected the data, cleaned it and made primary data mining via TCMISS, Tang SH made deep analysis on the data and wrote the paper.

Supplementary material

11655_2017_2957_MOESM1_ESM.pdf (130 kb)
Supplementary material to “Analysis on Composition Rules of Chinese Patent Drugs Treating Pain-Related Diseases Based on Data Mining Method”

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Copyright information

© The Chinese Journal of Integrated Traditional and Western Medicine Press and Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  1. 1.Institute of Chinese Materia MedicaChina Academy of Chinese Medical SciencesBeijingChina

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