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Chinese Journal of Integrative Medicine

, Volume 23, Issue 9, pp 648–653 | Cite as

Chinese medicine for outcomes in colorectal cancer patients: A retrospective clinical study

  • Feng-xia Lin
  • Li-feng Tian
  • Cai-yun Lei
  • Chen-chen Ding
  • Li Shi
  • Si-fang Zhang
Original Article

Abstract

Objective

To investigate the effect of Chinese medicine (CM) on survival of patients with stage II and III colorectal cancer (CRC).

Methods

A total of 295 patients who received chemotherapy were assigned to Group 1. The other 171 patients received the same chemotherapy treatment combined with the usage of CM Jianpi Jiedu Formula (健脾解毒方, JPJD) for more than 3 months (Group 2). Patients' survival time, relapse and metastasis, and cause of death were observed. Cox proportional hazard regression models were established for the analysis of the effect of independent factors on the survival prognosis of patients with CRC.

Results

The survival rate of patients in Group 2 was higher than that of Group 1 (P<0.05). Compared with Group 1, the mean survival time was prolonged by 5.594 months and the median survival time was prolonged by 6 months in Group 2 (P=0.004). Cox regression analysis indicated that CM combined with chemotherapy provided signifificant protective effect, as observed with the improvements in the survival rates of CRC patients (P<0.01).

Conclusion

CM can improve the survival rate in patients with stage II and III CRC.

Keywords

Chinese medicine integrative medicine Jianpi Jiedu Formula colorectal cancer survival period 

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Copyright information

© Chinese Association of the Integration of Traditional and Western Medicine and Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  • Feng-xia Lin
    • 1
    • 2
  • Li-feng Tian
    • 1
    • 3
  • Cai-yun Lei
    • 1
  • Chen-chen Ding
    • 1
  • Li Shi
    • 1
  • Si-fang Zhang
    • 1
  1. 1.Department of Integrated Traditional Chinese and Western MedicineThe Second Xiangya Hospital, Central South UniversityChangsha, HunanChina
  2. 2.Department of CardiologyBaoan Hospital of Traditional Chinese MedicineShenzhen, Guangdong ProvinceChina
  3. 3.Zhangmuba Army Sanatoriums of Hunan Military RegionChangsha, HunanChina

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