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Chinese Journal of Integrative Medicine

, Volume 22, Issue 9, pp 696–703 | Cite as

Non-invasive treatment to grade 1 essential hypertension by percutaneous laser and electric pulse to acupoint with music: A randomized controlled trial

  • Hong-rui Zhan (詹鸿锐)
  • Zhong-si Hong (洪仲思)
  • Yi-shen Chen (陈奕伸)
  • Hai-yu Hong (洪海裕)
  • Ze-bin Weng (翁泽滨)
  • Zhang-bin Yang (杨璋斌)Email author
  • Jing-li Shi (师晶丽)
  • Zhong-ben Chen (陈仲本)
Acupuncture Research

Abstract

Objective

To study a non-drug therapy for hypertension disease by combining percutaneous laser and electric pulse stimulation to acupoint with music, and to test the efficiency of the combining treatment to grade 1 essential hypertension.

Methods

A total of 174 patients with grade 1 essential hypertension were randomly assigned to 3 groups with a random number table after Chinese medicine (CM) syndrome differentiation: the photoelectric and musical treatment group (Group 1, with a self-developed multi-mode audio frequency pulse photoelectric therapeutic apparatus), acupuncture group (Group 2), and oral placebo group (Group 3), 58 cases per group. The curative effect of each group was evaluated by the changes of blood pressure and CM syndrome integral before and after treatment.

Results

Compared with Group 3, there were significant decrease of blood pressure and CM syndrome integral in Group 1 and Group 2 (P<0.01). Compared with Group 2, Group 1 showed the highest decrease in systolic pressure (P<0.017). The total effective rate of anti-hypertension in Group 1 (91.38%, 53/58) was significantly higher than that in Group 2 (74.13%, 43/58) and Group 3 (18.97%, 11/58, P<0.05 or P<0.01); and that in Group 2 was also significantly higher than that in Group 3 (P<0.01). There were significant difference in the total effective rate of CM syndrome integral in both Group 1 (93.10%, 54/58) and Group 2 (84.48%, 49/58) as compared with Group 3 (17.24%, 10/58, P<0.01), while there was no significant difference between Group 1 and Group 2 (P>0.05).

Conclusions

The multi-mode audio frequency pulse photoelectric therapeutic apparatus, combining music, laser and electric pulse stimulation, is clinically useful for grade 1 essential hypertension. This "three in one" therapy method is non-invasive, easy and simple to handle. It is expected to be popularized as a new alternative treatment.

Keywords

laser and electric pulse stimulation to acupoint musical treatment multi-mode audio frequency pulse photoelectric therapeutic apparatus grade 1 essential hypertension 

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References

  1. 1.
    Liu LS, ed. Hypertension. Beijing: People's Medical Publishing House; 2001:1–2.Google Scholar
  2. 2.
    Wolf-Maier K, Cooper RS, Banegas JR, Giampaoli S, Hense HW, Joffres M, et al. Hypertension prevalence and blood pressure levels in 6 European countries, Canada, and the United States. JAMA 2003;289:2363–2369.CrossRefPubMedGoogle Scholar
  3. 3.
    Li LM, Rao KQ, Kong LZ, Yao CH, Xiang HD, Zhai FY, et al. A description on the Chinese national nutrition and health survey in 2002. Chin J Epidemiol (Chin) 2005;26:478–484.Google Scholar
  4. 4.
    Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, He J. Global burden of hypertension: analysis of worldwide data. Lancet 2005;365:217–223.CrossRefPubMedGoogle Scholar
  5. 5.
    Xiong XD, ed. Internal medicine of Western medicine. Beijing: People's Medical Publishing House; 2012:143–152.Google Scholar
  6. 6.
    Ruan DJ, Yang ZQ. Hypertensive disease epidemiologic survey of Huairou district and risk factor analysis. Beijing Med J (Chin) 2010;32:516–518.Google Scholar
  7. 7.
    Lu ZY, Zhong NS, eds. Internal medicine. Beijing: People's Medical Publishing House; 2008:263–265.Google Scholar
  8. 8.
    Wang P. Necessity and feasibility of hypertension health promotion. Chin J Health Educat (Chin) 2004;20:334–336.Google Scholar
  9. 9.
    Jiang Y, Li LM. The review of prevention and control on community-based chronic disease. Chin J Prevent Control Chron Non-Communic Dis (Chin) 2000;8:49–51.Google Scholar
  10. 10.
    The ALLHAT Office and Coordinators for the ALLHAT Collacborative Group. Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs. diuretic: the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT). JAMA 2002;288:2981–2997.CrossRefGoogle Scholar
  11. 11.
    Song CX, Ouyang KH. The analysis about adverse reactions of antihypertensive drugs commonly used. Chin Foreign Med Res (Chin) 2012;27:142.Google Scholar
  12. 12.
    Qu YZ. Misunderstanding and processing methods on the treatment of hypertension. New Med (Chin) 2008;39:78–79,105.Google Scholar
  13. 13.
    Writing Group of Chinese Guidelines for the Management of Hypertension. 2010 Chinese guidelines for the management of hypertension. Chin J Cardiol (Chin) 2011;19:701–742.Google Scholar
  14. 14.
    Li Y, Xu LG, Deng YY, Liu H. Progress in clinical research on treatment of hypertension by acupuncture and moxibustion. J Changchun Univ Tradit Chin Med (Chin) 2006;22:71–72.Google Scholar
  15. 15.
    Sheng HY, Yan SX. Research progress on music therapy for treatment of hypertension patients. Chin Nursing Res (Chin) 2008;22:1701–1702.Google Scholar
  16. 16.
    Zhang J, Zhang YH, Bai Y. Study of music electroacupuncture. Chin Acupunct Moxibust (Chin) 2005;25:585–588.Google Scholar
  17. 17.
    He J, Peng YF, Mu KJ, Cheng ZH. Laser acupuncture theory and its clinical applications. Appl Laser (Chin) 2008;28:84–87.Google Scholar
  18. 18.
    Wang J, Xiong X. Evidence-based Chinese medicine for hypertension. Evid Based Complement Alternat Med 2013;2013:978398.PubMedPubMedCentralGoogle Scholar
  19. 19.
    Zheng XY, ed. Guiding principle of clinical research on new drugs of Chinese medicine (trial). Beijing: China Medical Science and Technology Press; 2002:73–77.Google Scholar
  20. 20.
    World Health Organization in the Western Pacific Region. WHO standard acupuncture point locations in the Western Pacific Region. Beijing: People's Medical Publishing House; 2010:28, 54,75,102,146,173, 204.Google Scholar
  21. 21.
    Yuwen Y, Shi NN, Wang LY, Xie YM, Han XJ, Lu AP. Development of clinical practice guidelines in 11 common diseases with Chinese medicine interventions in China. Chin J Integr Med 2012;18:112–119.CrossRefPubMedGoogle Scholar
  22. 22.
    Liu HN, Zhou Q, Guan L. Progress in research on hypertension by Chinese medicine. J Changchun Coll Tradit Chin Med (Chin) 2009;25:289–290.Google Scholar
  23. 23.
    Liu JY, Yang DH, Bai TY. The frequency analysis of clinical point in the acupuncture treatment of essential hypertension. J Shandong Univ Tradit Chin Med (Chin) 2009;3:215–216.Google Scholar
  24. 24.
    Wu YH, Qi ZG, You LX, Ouyang LX, Su HM, Wu BQ. Effect of needling Quchi and Taichong points on blood levels of endothelin and angiotension converting enzyme in patients with hypertension. Chin J Integr Tradit West Med (Chin) 2004;24:1080–1083.Google Scholar
  25. 25.
    Chen YL, Mo SL, Wu WK, Zhu YY, Luo HC, Chen JW, et al. Effect of electroacupuncture "Zusanli" on serum nitric oxide (NO) and plasma endothelin (ET) of spontaneous hypertension rats (SHR). Chin J Natur Med (Chin) 2002;4:14–16.Google Scholar
  26. 26.
    Schneider A, Weiland C, Enck P, Joos S, Streitberger K, Maser-Gluth C, et al. Neuroendocrinological effects of acupuncture treatment in patients with irritable bowel syndrome. Complement Ther Med 2007;15:255–263.CrossRefPubMedGoogle Scholar
  27. 27.
    Hwang DS, Kim HK, Seo JC, Shin IH, Kim DH, Kim YS. Sympathomodulatory effects of Saam acupuncture on heart rate variability in night-shift-working nurses. Complement Ther Med 2011;19 (Suppl 1):S33–S40.CrossRefPubMedGoogle Scholar
  28. 28.
    Li ZR, Shen MH, Peng YJ. Progress in researches on the effect of acupuncture in antagonizing oxygen stress. Chin J Integr Med 2005;11:156–160.CrossRefPubMedGoogle Scholar
  29. 29.
    Jin CN, Zhang TS, Ji LX, Tian YF. Survey of studies on mechanisms of acupuncture and moxibustion in decreasing blood pressure. Chin Acupunct Moxibust (Chin) 2007;27:467–470.Google Scholar
  30. 30.
    Sui JH, Xiao D. Recent studies on the mechanism of acupuncture treatment of hypertension. J Clin Acupunct Moxibust (Chin) 2000;12:43–45.Google Scholar
  31. 31.
    Bekiroglu T, Ovayolu N, Ergun Y, Ekerbicer HC. Effect of Turkish classical music on blood pressure: a randomized controlled trial in hypertensive elderly patients. Complement Ther Med 2013;21:147–154.CrossRefPubMedGoogle Scholar
  32. 32.
    Ruan JW, Wang CH, Liang Q, Lin KY, Han XL. The curative effect of music-regulated laser therapy and the quality of life of patients with primary hyper-tension. Chin J Physic Med Rehabilit (Chin) 2010;32:34–37.Google Scholar
  33. 33.
    Wang ZG, Shi MH, Song LM, Li XY, Tan YK, Tan RC. The effect of introvascular low intensity laser irradiation of blood on hemorheologic properties in diabetic rabbits. ACTA Laser Biol Sin (Chin) 1997;6:961–965.Google Scholar
  34. 34.
    Chen ZB, Song LJ, Wang ZG, Tang MR, Wu HQ. The effects of low intensity He-Ne laser irradiation and estrogen on ovariectomized rabbits' hemorheology. ACTA Laser Biol Sin (Chin) 2003;12:137–140.Google Scholar
  35. 35.
    Xiong GX, Song XW. Effects of semiconductor laser irradiation on erythrocyte rheology. Appl Laser (Chin) 2006;26:134–136.Google Scholar
  36. 36.
    Spodaryk K. The influence of low-power laser energy on red blood cell metabolism and deformability. Clin Hemorheol Microcirc 2001;25:145–151.PubMedGoogle Scholar
  37. 37.
    Yan HJ, Wan ZG. The analysis about dose and mechanism of laser irradiation on acupuncture point. ACTA Laser Biol Sin (Chin) 2006;15:550–551.Google Scholar
  38. 38.
    You C, Xiong X, Feng QC, Xie PC, Yi C, Chen ZB. Effects of pulse width modulation audio signals on blood pressure in hypertension model rats. Chin J Med Physics (Chin) 2008;25:527–528,533.Google Scholar
  39. 39.
    Gong WL, Huang SJ, Si G, Zhang KY, Chen ZB. The effects of multi-mode audio frequency pulse modulating laser together with electrical stimulation on blood pressure and hemorrheology of the spontaneously hpertensive rats. J Biomed Engineer (Chin) 2012;3:415–419.Google Scholar

Copyright information

© Chinese Association of the Integration of Traditional and Western Medicine and Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  • Hong-rui Zhan (詹鸿锐)
    • 1
  • Zhong-si Hong (洪仲思)
    • 2
  • Yi-shen Chen (陈奕伸)
    • 3
  • Hai-yu Hong (洪海裕)
    • 4
  • Ze-bin Weng (翁泽滨)
    • 5
  • Zhang-bin Yang (杨璋斌)
    • 6
    Email author
  • Jing-li Shi (师晶丽)
    • 6
  • Zhong-ben Chen (陈仲本)
    • 7
  1. 1.Department of Physical Medicine and RehabilitationThe Fifth Affiliated Hospital of Sun Yat-sen UniversityZhuhai, Guangdong ProvinceChina
  2. 2.Department of Infectious DiseasesThe Fifth Affiliated Hospital of Sun Yatsen UniversityZhuhai, Guangdong ProvinceChina
  3. 3.Department of PharmacyThe Fifth Affiliated Hospital of Sun Yat-sen UniversityZhuhai, Guangdong ProvinceChina
  4. 4.Department of OtorhinolaryngologyThe Fifth Affiliated Hospital of Sun Yat-sen UniversityZhuhai, Guangdong ProvinceChina
  5. 5.Department of General SurgeryThe Fifth Affiliated Hospital of Sun Yat-sen UniversityZhuhai, Guangdong ProvinceChina
  6. 6.Department of Traditional Chinese MedicineThe Fifth Affiliated Hospital of Sun Yat-sen UniversityZhuhai, Guangdong ProvinceChina
  7. 7.Department of Biomedical Engineering, Zhongshan School of MedicineSun Yat-sen UniversityGuangzhouChina

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