Chinese Journal of Integrative Medicine

, Volume 22, Issue 9, pp 696–703 | Cite as

Non-invasive treatment to grade 1 essential hypertension by percutaneous laser and electric pulse to acupoint with music: A randomized controlled trial

  • Hong-rui Zhan (詹鸿锐)
  • Zhong-si Hong (洪仲思)
  • Yi-shen Chen (陈奕伸)
  • Hai-yu Hong (洪海裕)
  • Ze-bin Weng (翁泽滨)
  • Zhang-bin Yang (杨璋斌)Email author
  • Jing-li Shi (师晶丽)
  • Zhong-ben Chen (陈仲本)
Acupuncture Research



To study a non-drug therapy for hypertension disease by combining percutaneous laser and electric pulse stimulation to acupoint with music, and to test the efficiency of the combining treatment to grade 1 essential hypertension.


A total of 174 patients with grade 1 essential hypertension were randomly assigned to 3 groups with a random number table after Chinese medicine (CM) syndrome differentiation: the photoelectric and musical treatment group (Group 1, with a self-developed multi-mode audio frequency pulse photoelectric therapeutic apparatus), acupuncture group (Group 2), and oral placebo group (Group 3), 58 cases per group. The curative effect of each group was evaluated by the changes of blood pressure and CM syndrome integral before and after treatment.


Compared with Group 3, there were significant decrease of blood pressure and CM syndrome integral in Group 1 and Group 2 (P<0.01). Compared with Group 2, Group 1 showed the highest decrease in systolic pressure (P<0.017). The total effective rate of anti-hypertension in Group 1 (91.38%, 53/58) was significantly higher than that in Group 2 (74.13%, 43/58) and Group 3 (18.97%, 11/58, P<0.05 or P<0.01); and that in Group 2 was also significantly higher than that in Group 3 (P<0.01). There were significant difference in the total effective rate of CM syndrome integral in both Group 1 (93.10%, 54/58) and Group 2 (84.48%, 49/58) as compared with Group 3 (17.24%, 10/58, P<0.01), while there was no significant difference between Group 1 and Group 2 (P>0.05).


The multi-mode audio frequency pulse photoelectric therapeutic apparatus, combining music, laser and electric pulse stimulation, is clinically useful for grade 1 essential hypertension. This "three in one" therapy method is non-invasive, easy and simple to handle. It is expected to be popularized as a new alternative treatment.


laser and electric pulse stimulation to acupoint musical treatment multi-mode audio frequency pulse photoelectric therapeutic apparatus grade 1 essential hypertension 


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Copyright information

© Chinese Association of the Integration of Traditional and Western Medicine and Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  • Hong-rui Zhan (詹鸿锐)
    • 1
  • Zhong-si Hong (洪仲思)
    • 2
  • Yi-shen Chen (陈奕伸)
    • 3
  • Hai-yu Hong (洪海裕)
    • 4
  • Ze-bin Weng (翁泽滨)
    • 5
  • Zhang-bin Yang (杨璋斌)
    • 6
    Email author
  • Jing-li Shi (师晶丽)
    • 6
  • Zhong-ben Chen (陈仲本)
    • 7
  1. 1.Department of Physical Medicine and RehabilitationThe Fifth Affiliated Hospital of Sun Yat-sen UniversityZhuhai, Guangdong ProvinceChina
  2. 2.Department of Infectious DiseasesThe Fifth Affiliated Hospital of Sun Yatsen UniversityZhuhai, Guangdong ProvinceChina
  3. 3.Department of PharmacyThe Fifth Affiliated Hospital of Sun Yat-sen UniversityZhuhai, Guangdong ProvinceChina
  4. 4.Department of OtorhinolaryngologyThe Fifth Affiliated Hospital of Sun Yat-sen UniversityZhuhai, Guangdong ProvinceChina
  5. 5.Department of General SurgeryThe Fifth Affiliated Hospital of Sun Yat-sen UniversityZhuhai, Guangdong ProvinceChina
  6. 6.Department of Traditional Chinese MedicineThe Fifth Affiliated Hospital of Sun Yat-sen UniversityZhuhai, Guangdong ProvinceChina
  7. 7.Department of Biomedical Engineering, Zhongshan School of MedicineSun Yat-sen UniversityGuangzhouChina

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