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Chinese Journal of Integrative Medicine

, Volume 25, Issue 10, pp 795–799 | Cite as

Astible Rivularis: Bioactive Compounds and Pharmacological Functions

  • Sunita TimalsenaEmail author
  • Prem Prasad Lamichhane
Review

Abstract

Astilbe rivularis Buch. Ham., a rhizomatous perennial herb of the Saxifragaceae family, has been listed in rare species. In traditional medicine the plant has been used for the treatment of ulcer, bleeding during child birth, inflammation, body ache, diarrhea, and dysentery. This article reviews and analyses the traditional use, pharmacological activities of the corresponding bioactive compounds, and toxicological data on A. rivularis species. A. rivularis has been used across Indian subcontinent to treat various human ailments. Its extract consists of alkaloids, flavonoids, coumarins and glycosides. These extracts as well as isolated bioactive compounds demonstrated various biological activities including antimicrobial, anti-peptic ulcer, anti-inflammatory, and antioxidant activity. Toxicological studies of the extract on brine shrimp larvae demonstrated mild toxicity; however no acute toxicity in mice. Although the pharmacological effect of A. rivularis has been poorly explored, the available data validated its use in ethnomedicine. To reveal the cryptic therapeutic potential of the species, research should focus on identification and mechanistic studies of the bioactive compounds.

Keywords

Astilbe rivularis ethnomedical pharmacological bioactive compounds toxicological 

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Notes

Acknowledgement

Timalsena S and Lamichhane PP were supported by Siriraj Graduate Scholarship and Siriraj Graduate Thesis Scholarship.

Author Contributions

Timalsena S and Lamichhane PP conducted this review. Both authors wrote the manuscript. Both read and approved the final version of the manuscript.

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Copyright information

© The Chinese Journal of Integrated Traditional and Western Medicine Press and Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  1. 1.Department of Pharmacology, Faculty of Medicine Siriraj HospitalMahidol UniversityBangkokThailand
  2. 2.Department of Microbiology, Faculty of Medicine Siriraj HospitalMahidol UniversityBangkokThailand

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