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Chinese Journal of Integrative Medicine

, Volume 25, Issue 11, pp 825–830 | Cite as

Observational Study of Chinese Medicine Syndrome Distribution in Patients with Acute Myocardial Infarction and Its Impact on Prognosis

  • Hong-min Zhu
  • Jing-min Zhou
  • Xue-juan Jin
  • Ming-qiang Fu
  • Ling-ti Zhu
  • Xiao-tong Cui
  • Yue Fan
  • Ding-fang Cai
  • Jun-bo GeEmail author
Original Article
  • 33 Downloads

Abstract

Objective

To investigate the distribution of Chinese medicine (CM) syndrome in patients with acute myocardial infarction (AMI) on admission and its impact on prognosis.

Methods

A total of 525 AMI patients were prospectively recruited and classifified into 4 groups based on their clinical characteristics: excess-heat, excess-cold, deficiency-heat and deficiency-cold syndromes. Major adverse cardiovascular events (MACEs) were followed up.

Results

The excess syndrome was more common than deficiency syndrome (72.95% vs. 27.05%; P<0.05). Totally 495 (94.29%) of 525 AMI patients were followed up (median 277 days). There were 59 (11.92%) MACEs. After adjusted with confounding factors in Cox regression models, the hazard ratio (95% confifidence interval) of excess-heat, excess-cold, defificiency-heat and defificiency-cold syndrome groups were 1, 1.25 (0.63, 2.49; P<0.05), 2.37 (1.14, 4.94; P<0.05), 3.76 (1.71, 8.28; P<0.05), respectively.

Conclusions

Excess syndrome was more common in AMI patients and had better prognosis, while defificiency-cold syndrome had the poorest prognosis. CM syndrome was of value in predicting long-term outcomes in AMI patients.

Keywords

acute myocardial infarction Chinese medicine syndrome prognosis 

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Notes

Acknowledgements

We thank all the staff members who provided help to the present study.

Author Contributions

Ge JB and Zhou JM conceived and designed the experiments. Fan Y, Zhu HM, FU Ming-qiang and Zhu LT performed the experiments. Jin XJ and Cui XT analyzed the data. Cai DF and Fan Y provided technical support. Zhu HM wrote the paper. Zhou JM revised the paper. Zhu HM and Zhou JM contributed equally to this work.

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Copyright information

© The Chinese Journal of Integrated Traditional and Western Medicine Press and Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  • Hong-min Zhu
    • 1
  • Jing-min Zhou
    • 1
  • Xue-juan Jin
    • 1
  • Ming-qiang Fu
    • 1
  • Ling-ti Zhu
    • 1
  • Xiao-tong Cui
    • 1
  • Yue Fan
    • 2
  • Ding-fang Cai
    • 2
  • Jun-bo Ge
    • 1
    Email author
  1. 1.Department of Cardiology, Zhongshan HospitalFudan UniversityShanghaiChina
  2. 2.Department of Integrated Traditional and Western Medicine, Zhongshan HospitalFudan UniversityShanghaiChina

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